NapaDol Tablet is a fixed-dose combination of Paracetamol 325 mg and Tramadol Hydrochloride 37.5 mg, formulated to provide effective relief from moderate to moderately severe pain. This combination offers dual-action analgesia by combining the well-established pain-relieving and antipyretic effects of Paracetamol with the centrally acting opioid analgesic properties of Tramadol. NapaDol is particularly useful when pain is not adequately controlled by non-opioid analgesics alone.

Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system, thereby reducing pain perception and fever. Tramadol Hydrochloride acts on the central nervous system by binding to opioid receptors and inhibiting the reuptake of norepinephrine and serotonin, which enhances pain inhibition pathways. The complementary mechanisms of action result in improved pain control with lower doses of each component, helping to balance efficacy and tolerability.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

NapaDol Tablet is indicated for the management of:

• Moderate to moderately severe pain

• Postoperative pain

• Musculoskeletal pain

• Back pain

• Joint pain and osteoarthritis-related pain

• Pain following injury or trauma

• Dental pain

It is intended for use in adults and adolescents, as prescribed by a healthcare professional.

Dosage and Administration

NapaDol Tablet is administered orally. The dosage and duration of treatment should be determined by a physician based on the severity of pain, patient response, and overall clinical condition. Tablets should be swallowed whole with water. Patients should strictly adhere to the prescribed dosing schedule and should not exceed the recommended dose to minimize the risk of adverse effects.

Key Benefits and Features

• Dual-action analgesia for enhanced pain relief

• Effective in pain not controlled by Paracetamol alone

• Combines opioid and non-opioid mechanisms

• Suitable for short-term management of moderate pain

• Convenient oral tablet formulation

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety and Precautions

NapaDol Tablet should be used with caution due to the presence of Tramadol. Prolonged use may lead to dependence or tolerance. Common side effects may include nausea, dizziness, drowsiness, constipation, or headache. The medicine should be used cautiously in patients with respiratory depression, epilepsy, liver or kidney impairment, and in those with a history of substance abuse. Concomitant use with alcohol or other central nervous system depressants should be avoided. Paracetamol overdose can cause serious liver damage; therefore, other Paracetamol-containing products should not be used simultaneously.

Storage Conditions

Store NapaDol Tablet in a cool, dry place away from moisture and direct sunlight. Keep out of reach of children.

Pharmaceutical Information

• Active ingredients: Paracetamol + Tramadol Hydrochloride

• Strength: 325 mg + 37.5 mg

• Dosage form: Tablet

NapaDol Tablet provides reliable and effective pain control through its dual-mechanism formulation. When used as prescribed, it offers balanced analgesia for patients experiencing moderate pain requiring stronger therapeutic support.