Naligram Suspension 300 mg/5 ml contains Nalidixic Acid, a synthetic quinolone antibiotic specifically formulated as an oral suspension for pediatric patients or adults who have difficulty swallowing tablets. It is primarily used for the treatment of urinary tract infections (UTIs) caused by susceptible Gram-negative bacteria. This liquid formulation allows for accurate dosing and ease of administration, especially in children.

Nalidixic Acid works by inhibiting bacterial DNA replication. It targets bacterial enzymes called DNA gyrase and topoisomerase IV, which are essential for bacterial cell division and replication. By interfering with these enzymes, Naligram effectively stops the growth of bacteria and promotes their elimination from the urinary tract. Being bactericidal, it actively kills the bacteria responsible for the infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Naligram Suspension 300 mg/5 ml is indicated for the treatment of:

• Acute uncomplicated urinary tract infections (UTIs)

• Cystitis and pyelonephritis caused by susceptible Gram-negative bacteria, including Escherichia coli and Proteus species

• Prophylaxis of recurrent UTIs in selected cases, under medical supervision

It should only be used for infections confirmed or strongly suspected to be caused by bacteria sensitive to nalidixic acid.

Dosage and Administration

The dosage of Naligram Suspension depends on the patient’s age, weight, and severity of the infection. For children, the dose is calculated based on body weight, usually ranging from 30 mg to 50 mg per kilogram per day divided into two to four doses, or as prescribed by a physician.

Shake the bottle well before each use to ensure uniform distribution of the medication. Measure the prescribed dose using a calibrated oral syringe or measuring spoon for accuracy. The suspension can be taken with or without food.

It is important to complete the full course of treatment, even if symptoms improve before finishing the medication, to ensure complete eradication of the infection and to prevent antibiotic resistance.

Precautions and Warnings

• Not recommended in patients with hypersensitivity to nalidixic acid or other quinolone antibiotics.

• Use with caution in patients with renal impairment; dose adjustments may be necessary.

• Adequate hydration is recommended to reduce the risk of crystalluria (crystals in urine).

• Avoid excessive exposure to sunlight or UV light, as photosensitivity reactions may occur.

• Inform the physician about any other medications being taken to avoid potential drug interactions.

• Not recommended for children under one year of age or during pregnancy and lactation unless specifically prescribed.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Naligram Suspension 300 mg/5 ml is generally well tolerated. Common side effects may include:

• Nausea and vomiting

• Diarrhea

• Mild abdominal discomfort

• Dizziness or headache

Rare but serious side effects may include hypersensitivity reactions, crystalluria, hematuria, or neurological symptoms such as seizures. Immediate medical attention is required if severe reactions occur.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Naligram Suspension 300 mg/5 ml provides effective and convenient therapy for urinary tract infections in pediatric patients and adults requiring liquid formulations. When used under medical supervision, it ensures rapid relief from infection symptoms and supports a full recovery.