Naftol Tablet 75 mg contains Naftopidil, an alpha-1 adrenergic receptor antagonist used primarily to manage benign prostatic hyperplasia (BPH). By selectively relaxing smooth muscles in the prostate and bladder neck, Naftopidil helps improve urine flow, reduce urinary urgency, and alleviate lower urinary tract symptoms associated with enlarged prostate. Its targeted action ensures effective relief with minimal impact on blood pressure compared to non-selective alpha-blockers.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Naftopidil 75 mg per tablet

Mechanism of Action

Naftopidil works by selectively blocking alpha-1 adrenergic receptors in the prostate, urethra, and bladder neck:

• Relaxes smooth muscles in the lower urinary tract
• Reduces urethral resistance and improves urine flow
• Alleviates urinary frequency, urgency, and nocturia
• Has limited effect on systemic blood pressure due to receptor selectivity

Indications

Naftol Tablet 75 mg is indicated for:

• Benign prostatic hyperplasia (BPH) in adult men
• Lower urinary tract symptoms (LUTS) including:
  • Difficulty initiating urination
  • Weak urine stream
  • Frequent urination
  • Nocturia (nighttime urination)
• Symptomatic relief of bladder outlet obstruction

Dosage and Administration

• Adults: 1 tablet (75 mg) once daily, preferably after a meal
• Swallow the tablet whole with water; do not crush or chew
• Take at the same time each day for consistent therapeutic effect
• Dose adjustment may be necessary in elderly patients or those with liver/kidney impairment
• Continuous therapy is usually required for sustained symptom relief

Benefits

• Improves urinary flow and reduces bladder outlet obstruction
• Relieves symptoms of BPH and lower urinary tract discomfort
• Selective alpha-1 blockade minimizes risk of hypotension
• Convenient once-daily dosing improves patient compliance
• Enhances quality of life in men with BPH

Side Effects

Common side effects:

• Dizziness or lightheadedness
• Headache
• Fatigue or drowsiness
• Mild gastrointestinal discomfort

Serious but rare side effects:

• Orthostatic hypotension (drop in blood pressure when standing)
• Palpitations or arrhythmias
• Allergic reactions (rash, itching, swelling)

Precautions

• Monitor blood pressure in patients with cardiovascular disorders
• Use with caution in patients with liver or kidney impairment
• Avoid driving or operating machinery if dizziness or drowsiness occurs
• Consult a physician before use in combination with other antihypertensive drugs

Contraindications

• Hypersensitivity to Naftopidil or any component of the tablet
• Severe liver or kidney disease
• History of orthostatic hypotension or uncontrolled hypotension

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Other antihypertensive medications may potentiate blood pressure-lowering effects
• Caution with drugs affecting CYP3A4 metabolism
• Avoid simultaneous use with other alpha-blockers unless prescribed

Storage

• Store below 30°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children.