Metorax Tablet 10 mg contains Methotrexate, a potent antimetabolite and immunosuppressive agent used to treat a variety of cancerous and autoimmune conditions. Methotrexate works by inhibiting dihydrofolate reductase, an enzyme essential for DNA synthesis, thereby slowing the growth of rapidly dividing cells.

This oral formulation allows precise dosing for chronic therapy in conditions such as rheumatoid arthritis, psoriasis, and certain types of cancer, under strict medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Methotrexate 10 mg

Mechanism of Action

Methotrexate is an antifolate drug that:

• Inhibits dihydrofolate reductase, blocking DNA, RNA, and protein synthesis

• Slows the proliferation of rapidly dividing cells, such as cancer cells and overactive immune cells

• Reduces inflammation in autoimmune disorders by modulating immune system activity

This dual action makes Methotrexate effective in both oncology and rheumatology.

Indications

Metorax Tablet 10 mg is indicated for:

• Acute lymphoblastic leukemia and other malignancies

• Rheumatoid arthritis in adults

• Psoriasis and other severe skin disorders

• Selected autoimmune diseases as prescribed by a healthcare professional

Dosage and Administration

• Take exactly as prescribed by a healthcare professional

• Typical dose varies widely based on condition, body surface area, and treatment protocol

• Swallow the tablet whole with water, with or after food to reduce gastrointestinal irritation

• Usually administered once weekly in chronic conditions like rheumatoid arthritis

• Regular monitoring of blood counts, liver, and kidney function is essential

Precautions

• Use with caution in patients with liver or kidney impairment

• Avoid in pregnancy and breastfeeding

• Monitor for bone marrow suppression, infections, and liver toxicity

• Do not use concurrently with drugs that may increase Methotrexate toxicity without medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Nausea, vomiting, or loss of appetite

• Mouth ulcers or gastrointestinal discomfort

• Fatigue or dizziness

Serious but rare side effects may include:

• Bone marrow suppression leading to low blood counts

• Liver toxicity or fibrosis

• Severe infections due to immunosuppression

• Pulmonary toxicity or pneumonitis

Immediate medical attention is required if unusual bleeding, severe infections, or breathing difficulties occur.

Storage

• Store below 25°C

• Keep in a dry place, away from sunlight

• Keep out of reach of children.