Metform ER Tablet 500 mg contains Metformin Hydrochloride in an extended-release (ER) formulation, designed for the effective management of type 2 diabetes mellitus. This formulation allows the medication to be released slowly over time, providing prolonged blood glucose control with fewer gastrointestinal side effects compared to immediate-release forms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Metformin Hydrochloride 500 mg (Extended Release)

Mechanism of Action

Metformin works by reducing glucose production in the liver, decreasing intestinal absorption of glucose, and enhancing insulin sensitivity in peripheral tissues. The extended-release formulation ensures a steady release of the drug, helping maintain consistent blood sugar levels throughout the day.

Indications

Metform ER Tablet 500 mg is indicated for:

• Management of type 2 diabetes mellitus
• Improving glycemic control in adults
• Patients requiring sustained blood sugar control
• Use as monotherapy or in combination with other oral antidiabetic drugs or insulin

Dosage and Administration

• Take once daily or as prescribed by a physician
• Should be taken with meals, preferably in the evening
• Swallow the tablet whole; do not crush, chew, or break it
• Dosage should be adjusted gradually to minimize gastrointestinal side effects

Benefits

• Provides prolonged and stable blood glucose control
• Reduced dosing frequency (once daily) improves patient compliance
• Lower risk of gastrointestinal side effects compared to immediate-release formulations
• Does not usually cause weight gain
• Low risk of hypoglycemia when used alone

Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Flatulence

Rare but serious side effect:

• Lactic acidosis (rare but serious condition requiring immediate medical attention)

Precautions

• Use cautiously in patients with kidney or liver impairment
• Regular monitoring of renal function is recommended
• Avoid excessive alcohol consumption
• Inform your doctor before any surgery or contrast imaging procedures
• Not recommended in severe renal dysfunction

Contraindications

• Severe renal impairment
• Metabolic acidosis, including diabetic ketoacidosis
• Known hypersensitivity to Metformin

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Metformin may interact with:

• Other antidiabetic medications
• Diuretics and corticosteroids
• Iodinated contrast agents

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.