Loreta Tablet 2.5 mg contains Letrozole, an aromatase inhibitor used primarily in the treatment of hormone receptor–positive breast cancer in postmenopausal women. It works by reducing estrogen levels in the body, thereby slowing or stopping the growth of estrogen-dependent breast cancer cells.

Letrozole is also used in certain cases for ovulation induction under specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Letrozole
• Strength: 2.5 mg
• Dosage Form: Oral tablet

Mechanism of Action

Letrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogen. This results in:

• Significant reduction in estrogen production
• Slowing of growth of estrogen-dependent tumors
• Suppression of hormone-driven cancer cell proliferation

Indications

Loreta Tablet is indicated for:

• Hormone receptor–positive breast cancer in postmenopausal women
• Adjuvant therapy in early breast cancer
• Advanced or metastatic breast cancer
• Off-label use in ovulation induction (under specialist supervision only)

Dosage and Administration

• Dosage is strictly as prescribed by an oncologist or specialist
• Commonly taken once daily with or without food
• Swallow whole with water
• Treatment duration depends on clinical condition and response
• Do not self-adjust dose

Benefits

• Reduces estrogen levels effectively
• Helps slow or prevent progression of hormone-sensitive breast cancer
• Once-daily convenient dosing
• Useful in both early and advanced stages of disease
• May be used in fertility treatment protocols under supervision

Side Effects

Common side effects may include:

• Hot flashes
• Joint and muscle pain
• Fatigue
• Headache
• Nausea
• Increased sweating

Less common but serious effects:

• Bone thinning (osteoporosis)
• Increased cholesterol levels
• Mood changes
• Allergic reactions

Precautions and Warnings

• Use only under specialist supervision
• Not for use in premenopausal women unless advised
• Monitor bone density during long-term therapy
• Caution in patients with liver impairment
• Not recommended during pregnancy or breastfeeding
• May affect fertility and hormonal balance

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Contraindicated
• Lactation: Contraindicated
• Pediatrics: Not recommended
• Elderly: Commonly used in postmenopausal women with monitoring

Storage

• Store below 25°C
• Protect from moisture and light
• Keep in original packaging
• Keep out of reach of children.