Liptor Tablet 10 mg contains Atorvastatin Calcium, a potent HMG-CoA reductase inhibitor (statin), used to lower cholesterol and triglycerides in adults. It is primarily prescribed for patients with hyperlipidemia, mixed dyslipidemia, or elevated cardiovascular risk. By inhibiting HMG-CoA reductase, the enzyme responsible for cholesterol synthesis in the liver, Liptor reduces low-density lipoprotein (LDL-C) and total cholesterol while modestly increasing high-density lipoprotein (HDL-C).

Liptor is also effective in preventing atherosclerotic cardiovascular disease, including myocardial infarction, stroke, and angina, especially in patients with multiple risk factors such as diabetes, hypertension, or smoking. The tablet provides a convenient once-daily dosing regimen, making it easy for patients to adhere to long-term therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Liptor Tablet 10 mg is indicated for:

• Primary hypercholesterolemia (heterozygous familial and non-familial) to reduce elevated LDL-C

• Mixed dyslipidemia to lower total cholesterol, LDL-C, and triglycerides

• Prevention of cardiovascular events in patients with or at high risk of coronary heart disease

• Homozygous familial hypercholesterolemia as part of adjunct therapy, including LDL apheresis

• Hypertriglyceridemia in patients with elevated triglycerides

Therapeutic Class

• HMG-CoA reductase inhibitor (statin)

Pharmacology

Atorvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis. This leads to:

• Reduced intrahepatic cholesterol synthesis

• Upregulation of LDL receptors, increasing clearance of LDL from plasma

• Decreased levels of apolipoprotein B-containing lipoproteins

• Modest increase in HDL-C and decrease in triglycerides

By lowering LDL-C and other atherogenic lipoproteins, Liptor slows the progression of atherosclerosis and reduces the risk of cardiovascular events.

Dosage & Administration

• Adults: Typically, 10 mg once daily in the evening, with or without food

• Dose can be adjusted depending on lipid levels, up to a maximum of 80 mg per day

• Periodic lipid panel monitoring is recommended to assess response

• May be used as monotherapy or in combination with other lipid-lowering agents

Contraindications

• Known hypersensitivity to atorvastatin or any excipients

• Active liver disease or unexplained persistent elevations of hepatic transaminases

• Pregnancy and lactation

Side Effects

Common side effects include:

• Headache, fatigue, nausea, diarrhea, abdominal pain

• Mild elevations in liver enzymes

• Rare: myopathy, rhabdomyolysis, or severe liver toxicity

Patients should report unexplained muscle pain or weakness, especially when accompanied by malaise or fever.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Monitor liver function tests before starting and periodically during therapy

• Use with caution in patients with renal impairment

• Avoid grapefruit juice, which can increase the risk of side effects

• Caution when used with medications that interact with CYP3A4

Pregnancy & Lactation

• Contraindicated during pregnancy and breastfeeding due to potential fetal harm

Storage

Store below 30°C in a dry place, protected from light, and keep out of reach of children.

Liptor Tablet 10 mg is a safe and effective option for long-term management of high cholesterol and cardiovascular risk, supporting heart health through proven lipid-lowering effects and reduction of atherosclerotic complications.