Linajen Tablet 5 mg contains Linagliptin, an oral antidiabetic medicine belonging to the DPP-4 inhibitor class. It is used in the management of type 2 diabetes mellitus to help control blood glucose levels in adults when diet, exercise, and lifestyle changes alone are not sufficient.

Linagliptin works by enhancing the body’s natural ability to regulate blood sugar in a glucose-dependent manner, making it a well-tolerated option for long-term diabetes management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Linagliptin
• Strength: 5 mg
• Dosage Form: Oral tablet

Mechanism of Action

Linagliptin inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), which leads to:

• Increased levels of incretin hormones (GLP-1 and GIP)
• Enhanced insulin secretion in response to meals
• Reduced glucagon secretion from the liver
• Improved post-meal and fasting blood glucose control

Its glucose-dependent mechanism helps reduce the risk of hypoglycemia when used alone.

Indications

Linajen Tablet 5 mg is indicated for:

• Type 2 diabetes mellitus
• Patients inadequately controlled with diet and exercise alone
• Add-on therapy with other antidiabetic medicines (e.g., metformin, insulin, sulfonylureas)
• Patients requiring improved postprandial glucose control

Dosage and Administration

• Usual dose: 5 mg once daily
• Can be taken with or without food
• Swallow whole with water
• Dose adjustment is generally not required in renal impairment
• Should be taken regularly for optimal glycemic control

Benefits

• Improves both fasting and post-meal blood glucose levels
• Once-daily convenient dosing
• Low risk of hypoglycemia when used alone
• Weight neutral (does not typically cause weight gain)
• Suitable for use in combination therapy
• Well tolerated in long-term use

Side Effects

Common side effects may include:

• Nasopharyngitis (cold-like symptoms)
• Headache
• Cough
• Mild gastrointestinal discomfort

Less common but serious effects:

• Pancreatitis (rare)
• Severe allergic reactions
• Joint pain (rare reports)
• Hypoglycemia (mainly when combined with insulin or sulfonylureas)

Precautions and Warnings

• Use only under medical supervision
• Monitor blood glucose regularly
• Caution when used with insulin or sulfonylureas due to hypoglycemia risk
• Discontinue if symptoms of pancreatitis occur (severe abdominal pain)
• Not recommended for type 1 diabetes or diabetic ketoacidosis

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly needed and prescribed
• Lactation: Consult physician before use
• Pediatrics: Not recommended
• Elderly: Generally safe without dose adjustment

Storage

• Store below 25°C
• Protect from moisture and light
• Keep in original packaging
• Keep out of reach of children.