Jupitavir Tablet 150 mg + 100 mg is an oral antiviral medication formulated for the treatment of mild to moderate COVID-19 in adults who are at high risk of progression to severe disease. It contains a fixed-dose combination of Nirmatrelvir 150 mg and Ritonavir 100 mg, which work together to inhibit viral replication and reduce the severity of infection when administered early in the course of the disease.

COVID-19 is caused by the SARS-CoV-2 virus, which relies on specific viral enzymes for replication inside the human body. Jupitavir Tablet targets these critical enzymes, helping to limit viral multiplication, reduce viral load, and lower the risk of hospitalization or severe outcomes. This medication is intended for use under medical supervision and should be started as soon as possible after diagnosis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Nirmatrelvir 150 mg

• Ritonavir 100 mg

Pharmacology and Mechanism of Action

Nirmatrelvir is a SARS-CoV-2 protease inhibitor that blocks the activity of the viral 3CL protease enzyme. This enzyme is essential for viral replication. By inhibiting it, Nirmatrelvir prevents the virus from producing functional proteins, thereby stopping further replication within host cells.

Ritonavir acts primarily as a pharmacokinetic enhancer. It inhibits the CYP3A enzyme responsible for metabolizing Nirmatrelvir, thereby increasing and prolonging its plasma concentration. This combination ensures effective antiviral levels are maintained in the body for optimal therapeutic action.

Together, these agents provide a potent antiviral effect when used in the early stages of COVID-19 infection.

Indications

Jupitavir Tablet is indicated for:

• Treatment of mild to moderate COVID-19 infection in adults

• Patients with confirmed SARS-CoV-2 infection

• Individuals at high risk of developing severe COVID-19, including those with chronic medical conditions

The treatment should be initiated within the first few days of symptom onset for maximum benefit.

Dosage and Administration

Jupitavir Tablet should be taken strictly as prescribed by a registered medical practitioner. The usual dosing regimen and duration depend on clinical guidelines and patient-specific factors such as age, renal function, and overall health status.

Tablets are taken orally with water and may be taken with or without food. Completing the full course of therapy is essential, even if symptoms improve earlier.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not recommended for patients with severe liver or kidney impairment unless advised by a physician.

• Ritonavir has significant drug–drug interactions; patients must inform their healthcare provider about all current medications.

• Use during pregnancy or breastfeeding should be based on a careful risk–benefit assessment by a healthcare professional.

• Not intended for use as pre-exposure or post-exposure prophylaxis for COVID-19.

• Monitor for side effects such as altered taste, gastrointestinal discomfort, or liver enzyme changes.

Storage Instructions

Store Jupitavir Tablet in a cool, dry place away from direct sunlight. Keep out of reach of children.