Intracef DS Suspension 250 mg/5 ml contains Cephradine, a first-generation cephalosporin antibiotic presented in a double-strength (DS) oral suspension. This formulation is designed to deliver a higher dose of cephradine in a convenient liquid form, making it suitable for children who require higher doses and for adults who prefer oral suspension over solid dosage forms. Intracef DS Suspension is effective in the treatment of a wide range of mild to moderate bacterial infections caused by susceptible organisms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Cephalosporin Antibiotics
Beta-lactam Antibacterial Agent

Composition

Each 5 ml of reconstituted suspension contains Cephradine 250 mg.

Indications

Intracef DS Suspension 250 mg/5 ml is indicated for the treatment of infections caused by sensitive bacteria, including:

• Upper and lower respiratory tract infections such as tonsillitis, pharyngitis, bronchitis, and pneumonia

• Ear, nose, and throat infections including otitis media and sinusitis

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

The double-strength formulation is particularly useful when higher oral doses are required for effective infection control.

Pharmacology

Cephradine is a bactericidal cephalosporin antibiotic that inhibits bacterial cell wall synthesis. It acts by binding to penicillin-binding proteins, disrupting the formation of the peptidoglycan layer of the bacterial cell wall. This results in weakening of the cell wall and eventual bacterial cell death. Cephradine is stable against many beta-lactamase enzymes, allowing it to remain active against a broad range of common pathogens. Following oral administration, it is well absorbed and widely distributed in body tissues and fluids.

Dosage and Administration

The dosage of Intracef DS Suspension 250 mg/5 ml depends on the patient’s age, body weight, severity of infection, and renal function.

• Reconstitute the suspension as per instructions before use

• Shake well before each dose to ensure uniform drug distribution

• Administer the prescribed dose at regular intervals

Patients should complete the full course of therapy even if symptoms improve earlier.

Contraindications

Intracef DS Suspension is contraindicated in patients with:

• Known hypersensitivity to cephradine or other cephalosporin antibiotics

• History of severe allergic reactions to beta-lactam antibiotics

Precautions and Warnings

• Use with caution in patients with renal impairment; dosage adjustment may be required

• Patients with a history of penicillin allergy should be monitored closely due to possible cross-reactivity

• Prolonged use may result in overgrowth of non-susceptible organisms

Adverse Effects

Intracef DS Suspension is generally well tolerated. Possible adverse effects include:

• Nausea

• Vomiting

• Diarrhea

• Abdominal discomfort

• Skin rash or allergic reactions

Most adverse effects are mild and reversible.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Caution is advised when used with:

• Nephrotoxic medicines

• Oral anticoagulants, which may require monitoring of coagulation parameters

Storage

Store the dry powder in a cool and dry place. After reconstitution, store as directed and use within the recommended period. Keep out of reach of children.

Conclusion

Intracef DS Suspension 250 mg/5 ml is an effective double-strength oral cephalosporin antibiotic offering reliable treatment for a variety of bacterial infections. Its higher concentration, liquid formulation, and good tolerability make it a practical choice for patients requiring higher oral doses.