Intracef Capsule 500 mg contains Cephradine, a first-generation cephalosporin antibiotic with broad antibacterial activity against many gram-positive and selected gram-negative organisms. It is widely used for the treatment of mild to moderate bacterial infections affecting different parts of the body. Due to its reliable efficacy, oral convenience, and favorable safety profile, Intracef Capsule 500 mg is commonly prescribed in routine clinical practice.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Cephalosporin Antibiotics
Beta-lactam Antibacterial Agent

Composition

Each capsule contains Cephradine 500 mg.

Indications

Intracef Capsule 500 mg is indicated for the treatment of infections caused by susceptible bacteria, including:

• Upper and lower respiratory tract infections such as tonsillitis, pharyngitis, sinusitis, bronchitis, and pneumonia

• Urinary tract infections

• Skin and soft tissue infections

• Ear, nose, and throat infections

• Bone and joint infections

• Other bacterial infections as determined by clinical evaluation

It is suitable for patients who require higher oral doses for effective infection control.

Pharmacology

Cephradine is a bactericidal antibiotic that exerts its effect by inhibiting bacterial cell wall synthesis. It interferes with the formation of the peptidoglycan layer of the bacterial cell wall, leading to structural instability and eventual cell death. Cephradine is resistant to many beta-lactamases produced by bacteria, which helps maintain its antibacterial activity. After oral administration, it is rapidly absorbed and distributed to various tissues and body fluids, achieving effective therapeutic concentrations.

Dosage and Administration

The dosage and duration of treatment with Intracef Capsule 500 mg depend on the type and severity of infection and the patient’s clinical condition.

• Usually administered in divided doses during the day

• Capsules should be taken with adequate water and may be taken with or without food

Patients should complete the full prescribed course even if symptoms improve earlier.

Contraindications

Intracef Capsule 500 mg is contraindicated in patients with:

• Known hypersensitivity to cephradine or other cephalosporins

• History of severe allergic reactions to beta-lactam antibiotics

Precautions and Warnings

• Use with caution in patients with renal impairment; dose adjustment may be necessary

• Patients with a history of penicillin allergy should be monitored carefully due to potential cross-sensitivity

• Prolonged use may lead to superinfection with non-susceptible organisms

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Adverse Effects

Intracef Capsule 500 mg is generally well tolerated. Possible adverse effects include:

• Nausea

• Vomiting

• Diarrhea

• Abdominal discomfort

• Skin rash or hypersensitivity reactions

Most adverse effects are mild and resolve after discontinuation of therapy.

Drug Interactions

Caution is advised when used concomitantly with:

• Nephrotoxic drugs

• Oral anticoagulants, as monitoring of coagulation parameters may be required

Storage

Store in a cool and dry place, protected from light and moisture. Keep out of reach of children.

Conclusion

Intracef Capsule 500 mg is a dependable oral cephalosporin antibiotic that provides effective treatment for a wide range of bacterial infections. Its broad spectrum of activity, higher dosage strength, and good tolerability make it an important option for managing infections where oral antibiotic therapy is appropriate.