IntraCal 400 mg contains Calcium Orotate, a highly bioavailable calcium supplement used to prevent and treat calcium deficiency in the body. Calcium Orotate combines calcium with orotic acid, which enhances the transport and absorption of calcium into cells, particularly in bone tissue. It supports bone health, cartilage maintenance, cardiovascular efficiency, cognitive function, and overall metabolic processes.

IntraCal 400 mg is suitable for individuals with low calcium levels, bone loss conditions, premenstrual syndrome (PMS), pregnant or nursing women, and those recovering from orthopedic surgeries.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Minerals in bone formation

• Specific mineral preparations

Composition

• Calcium Orotate 400 mg per tablet

Indications

IntraCal 400 mg is indicated for:

• Prevention and treatment of low blood calcium levels

• Hypoparathyroidism

• Latent tetany

• Recovery after hip joint plastic surgery

• Support in inflammatory diseases such as arthritis and spondylitis

• Pregnant and lactating women to meet increased calcium needs

• Relief of Premenstrual Syndrome (PMS) symptoms

• Appetite suppression to aid in weight control

• Mood swings and cognitive enhancement

• Cardiac protection by improving cardiac muscle efficiency

• Bone disorders due to calcium deficiency, including:

  • Osteoporosis (postmenopausal, juvenile, senile)

  • Osteomalacia

  • Rickets

Pharmacology

Calcium Orotate is a calcium salt of orotic acid. Orotic acid acts as a carrier, facilitating calcium transport through cellular membranes, which allows for higher intracellular calcium uptake, especially in bones and cartilage. Additionally, orotic acid participates in DNA and RNA synthesis, supporting cellular growth and repair. This formulation ensures calcium is efficiently absorbed and utilized by the body, enhancing bone density and overall musculoskeletal health.

Dosage and Administration

• Calcium Orotate 400 mg: 2–3 tablets daily with meals, or as directed by a physician

• Calcium Orotate 740 mg: 1–2 tablets daily with meals, or as directed by a physician

The tablets should be taken with food to improve absorption and minimize gastrointestinal discomfort.

Drug Interactions

• Calcium may reduce absorption of: bisphosphonates, quinolone and tetracycline antibiotics, levothyroxine, phenytoin, and tiludronate disodium

• Thiazide diuretics may increase the risk of hypercalcemia and hypercalciuria when taken with calcium supplements

Contraindications

Do not use IntraCal 400 mg in patients with:

• Kidney stones or kidney disease

• Hyperparathyroidism

• Elevated blood or urine calcium levels

• Severe dehydration

Side Effects

• Common: bloating and abdominal swelling

• Less frequent: constipation, nausea, vomiting, headache, increased thirst or urination

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Check for allergies before use; inactive ingredients may cause reactions

• Use caution in patients with kidney disease, kidney stones, low stomach acid, heart disease, pancreatic disorders, sarcoidosis, or malabsorption syndromes

• Consult a physician if symptoms persist or side effects become serious

Pregnancy and Lactation

• Safe under medical supervision; supplementation helps prevent pregnancy-related high blood pressure and supports calcium needs during lactation

Overdose

Symptoms of overdose may include nausea, vomiting, loss of appetite, constipation, headache, weakness, or weight loss. Seek medical advice if these occur.

Storage Conditions

• Store below 30°C in a cool, dry place, away from light and moisture

• Keep out of reach of children.