Insul N Injection 40 IU/ml contains recombinant DNA (rDNA) human insulin, a short-acting insulin used for the management of diabetes mellitus. It is designed to control elevated blood glucose levels, especially after meals, and is commonly used as part of individualized insulin therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Insulin Human (rDNA) 40 IU/ml

Mechanism of Action

Insulin Human (rDNA) acts by replacing or supplementing the natural insulin produced by the pancreas. It promotes the uptake of glucose into muscle and fat tissues and reduces glucose production in the liver. This helps in lowering elevated blood sugar levels, particularly after food intake. As a short-acting insulin, it is primarily effective in controlling postprandial glucose spikes.

Indications

Insul N Injection is indicated for:

• Type 1 diabetes mellitus
• Type 2 diabetes mellitus when oral antidiabetic agents are insufficient
• Control of post-meal (postprandial) hyperglycemia
• Diabetic ketoacidosis (under hospital supervision)
• Gestational diabetes requiring insulin therapy
• Management of hyperglycemia in hospitalized patients

Dosage and Administration

• Administered via subcutaneous injection
• May be given intravenously in emergency hospital settings under medical supervision
• Usually injected 30 minutes before meals
• Dosage is individualized based on blood glucose levels, diet, and physician guidance
• Injection sites include abdomen, thigh, or upper arm
• Rotate injection sites regularly to avoid tissue changes

Possible Side Effects

Common side effects include:

• Hypoglycemia (low blood sugar)
• Weight gain
• Injection site reactions such as redness, swelling, or irritation
• Lipodystrophy at injection sites

Less common but serious effects:

• Severe hypoglycemia (confusion, seizures, unconsciousness)
• Allergic reactions
• Hypokalemia (low potassium levels)

Precautions

• Regular blood glucose monitoring is essential
• Do not skip meals after insulin administration
• Alcohol consumption may increase risk of hypoglycemia
• Dose adjustments may be required during illness, stress, or dietary changes
• Use cautiously in patients with kidney or liver impairment

Contraindications

• Hypoglycemia episodes
• Known hypersensitivity to human insulin or any component of the formulation

Drug Interactions

• Corticosteroids may increase blood glucose levels
• Beta-blockers may mask symptoms of hypoglycemia
• Oral antidiabetic agents may enhance insulin effect
• Thyroid hormones and diuretics may affect glucose control

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a refrigerator at 2°C to 8°C
• Do not freeze
• Protect from heat and direct sunlight
• Once in use, may be kept at room temperature for a limited period as per instructions

Important Notes

Insul N Injection 40 IU/ml (rDNA Human Insulin) is a short-acting insulin formulation used to effectively manage blood glucose levels, particularly after meals. Proper dose timing, diet control, and regular monitoring are essential for safe and effective diabetes management.