Ibrucon Capsule 140 mg contains Ibrutinib, a targeted anticancer medication used in the treatment of certain blood cancers. It belongs to a class of drugs known as Bruton’s tyrosine kinase (BTK) inhibitors, which work by blocking signals that help cancer cells grow and survive. Ibrutinib is widely used in conditions such as chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), and other B-cell malignancies.

This medicine is used under specialist supervision and plays a key role in modern targeted cancer therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Ibrutinib 140 mg

Mechanism of Action

Ibrutinib selectively inhibits Bruton’s tyrosine kinase (BTK), an enzyme essential for B-cell receptor signaling. By blocking BTK, it disrupts pathways involved in the proliferation, survival, and migration of malignant B cells. This leads to reduced tumor growth and promotes cancer cell death.

Indications

Ibrucon Capsule 140 mg is indicated for:

• Chronic lymphocytic leukemia (CLL)
• Mantle cell lymphoma (MCL)
• Waldenström’s macroglobulinemia
• Marginal zone lymphoma
• Chronic graft-versus-host disease (as prescribed)

Dosage and Administration

• To be taken orally as prescribed by an oncologist
• Usually taken once daily at the same time each day
• Swallow whole with water; do not open, crush, or chew
• Can be taken with or without food
• Treatment continues as long as clinical benefit is observed

Contraindications

Ibrucon Capsule should not be used in:

• Known hypersensitivity to Ibrutinib
• Pregnancy and breastfeeding unless clearly advised
• Severe hepatic impairment without specialist supervision

Side Effects

Common side effects include:

• Diarrhea
• Fatigue
• Nausea
• Bruising or bleeding tendency
• Muscle and joint pain
• Rash

Serious side effects may include:

• Severe bleeding events
• Atrial fibrillation
• Infections
• Cytopenias (low blood cell counts)

Precautions

• Regular monitoring of blood counts is essential
• Use cautiously in patients with bleeding disorders
• Monitor for cardiac symptoms such as irregular heartbeat
• Avoid infections and maintain hygiene
• Use effective contraception during treatment
• Avoid grapefruit products as they may increase drug levels

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Ibrucon Capsule may interact with:

• Strong CYP3A4 inhibitors or inducers
• Anticoagulants and antiplatelet drugs (increased bleeding risk)
• Antifungal and antibiotic medications
• Herbal products like St. John’s Wort

Storage Conditions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.