Hison Injection 100 mg/2 ml contains Hydrocortisone, a corticosteroid widely used for its potent anti-inflammatory and immunosuppressive properties. It is an essential medication in hospital and clinical settings for the management of severe allergic reactions, adrenal insufficiency, inflammatory disorders, and other conditions that require rapid corticosteroid therapy. Hydrocortisone mimics the action of naturally occurring cortisol, helping regulate inflammation, immune responses, and metabolic functions.

Hison Injection is specifically formulated for parenteral use, providing fast and effective relief in acute situations. Its injectable form ensures rapid absorption and onset of action, making it particularly suitable for emergency use, including shock, severe allergic reactions, and adrenal crisis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Hydrocortisone 100 mg per 2 ml
• Dosage Form: Injectable solution
• Route of Administration: Intravenous (IV) or Intramuscular (IM)

Indications

Hison Injection 100 mg/2 ml is indicated for:

• Acute and chronic inflammatory disorders, including severe arthritis, dermatologic conditions, and respiratory inflammations
• Management of severe allergic reactions such as anaphylaxis and angioedema
• Adrenal insufficiency and adrenal crisis where immediate corticosteroid replacement is necessary
• Autoimmune diseases and conditions requiring immunosuppression
• Shock or other critical conditions associated with inflammation or immune dysregulation

This broad range of indications makes Hison Injection a versatile and vital therapeutic agent in both emergency and routine clinical care.

Mechanism of Action

Hydrocortisone is a glucocorticoid that works by:

• Suppressing the release of inflammatory mediators, reducing swelling, redness, and pain
• Decreasing capillary permeability, preventing fluid accumulation in tissues
• Inhibiting overactive immune responses in autoimmune or hypersensitivity conditions
• Supporting metabolic processes by maintaining glucose, protein, and fat metabolism

By mimicking endogenous cortisol, Hison Injection restores physiological balance in conditions of adrenal insufficiency and provides rapid control of inflammatory and allergic processes.

Dosage and Administration

• Administered by trained healthcare professionals via IM or IV injection
• Dosage varies depending on the condition, severity, and patient response
• Single doses or tapering regimens may be used for acute or prolonged therapy
• Continuous monitoring of vital signs, blood pressure, blood glucose, and electrolyte levels is recommended
• Careful adjustment may be necessary in patients with diabetes, hypertension, or heart disease

Benefits

• Provides rapid relief from inflammation, pain, and allergic reactions
• Effective in managing acute adrenal insufficiency and adrenal crisis
• Supports treatment of autoimmune and inflammatory disorders
• Suitable for emergency and hospital settings
• Flexible dosing allows tailored therapy based on patient needs

Possible Side Effects

Common side effects:

• Mild irritation at the injection site
• Temporary fluid retention and mild swelling
• Elevated blood sugar levels
• Mood changes, insomnia, or restlessness

Rare but serious side effects:

• Severe allergic reactions
• Hypertension or exacerbation of heart failure
• Immune suppression leading to increased risk of infections
• Adrenal suppression with prolonged use

Immediate medical attention is required if severe adverse reactions occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with diabetes, hypertension, or cardiovascular disease
• Avoid abrupt discontinuation after prolonged therapy to prevent adrenal insufficiency
• Monitor for infections during prolonged use
• Use only under professional medical supervision, particularly in pregnancy or breastfeeding
• Store out of reach of children

Storage

• Store below 30°C in a cool, dry place
• Protect from light and freezing
• Keep the vial tightly closed when not in use.