Gynest Vaginal Cream 0.10% contains Estriol, a naturally occurring estrogen hormone used for the local treatment of symptoms associated with estrogen deficiency, particularly during and after menopause. This vaginal formulation is designed to relieve discomfort caused by vaginal atrophy, dryness, irritation, and inflammation resulting from reduced estrogen levels.

During menopause, decreased estrogen production can lead to thinning, dryness, and reduced elasticity of vaginal tissues. These changes may cause symptoms such as itching, burning, painful intercourse, and increased susceptibility to infections. Gynest Vaginal Cream provides localized estrogen therapy, helping restore the health and integrity of the vaginal lining while minimizing systemic absorption.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each gram of vaginal cream contains:

• Estriol 0.10%

Mechanism of Action

Estriol is a weak natural estrogen that acts directly on estrogen receptors in vaginal tissues. When applied intravaginally, it helps:

• Restore thickness and elasticity of vaginal epithelium

• Improve natural lubrication

• Increase blood flow to vaginal tissues

• Normalize vaginal pH

• Reduce symptoms of dryness, irritation, and discomfort

Because it is applied locally, the action is mainly confined to the vaginal area, reducing the likelihood of systemic hormonal effects compared to oral estrogen therapy.

Indications

Gynest Vaginal Cream 0.10% is indicated for:

• Treatment of vaginal atrophy due to estrogen deficiency

• Relief of vaginal dryness, itching, and burning

• Painful intercourse associated with menopausal changes

• Pre- and post-operative treatment in postmenopausal women (as advised by a physician)

• Supportive therapy for recurrent vaginal discomfort related to hormonal imbalance

Benefits

• Provides targeted relief from menopausal vaginal symptoms

• Restores natural moisture and elasticity

• Helps maintain healthy vaginal pH

• Improves comfort during daily activities and intimacy

• Localized action with minimal systemic exposure

Dosage and Administration

The dosage and duration of treatment should be determined by a qualified healthcare professional. Generally, a small amount of cream is applied intravaginally using the provided applicator, usually once daily at bedtime during the initial phase of treatment. After improvement, the frequency may be reduced to a maintenance dose as directed by the physician.

Hands should be washed before and after application. Follow the doctor’s instructions carefully for best results.

Precautions

• Not recommended in patients with known or suspected estrogen-dependent tumors

• Inform your doctor about any history of breast cancer, uterine cancer, or thromboembolic disorders

• Use with caution in patients with liver disease

• Regular medical check-ups are advised during prolonged therapy

• Not intended for use during pregnancy unless specifically prescribed

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Gynest Vaginal Cream is generally well tolerated. Mild side effects may include:

• Local irritation or itching

• Vaginal discharge

• Mild breast tenderness (rare)

If severe reactions or unusual symptoms occur, consult a healthcare professional promptly.

Storage

Store below 30°C in a cool, dry place. Protect from light. Keep out of reach of children.

Gynest Vaginal Cream 0.10% offers effective and localized estrogen therapy for relieving menopausal vaginal symptoms and improving overall vaginal health under medical supervision.