Gensulin R Injection 100 IU/ml contains Insulin Human [rDNA], a short-acting human insulin produced using recombinant DNA technology. It is used for effective control of blood glucose levels in patients with diabetes mellitus. Gensulin R is particularly suitable for managing postprandial hyperglycemia and for situations where rapid insulin action is required. The injection is administered under medical supervision as part of an individualized diabetes management plan.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Insulin Human [rDNA] (Regular insulin)

• Strength: 100 IU/ml

Therapeutic Class

• Antidiabetic agent

• Short-acting human insulin

Indications

Gensulin R Injection is indicated for:

• Type 1 diabetes mellitus

• Type 2 diabetes mellitus when insulin therapy is required

• Control of postprandial blood glucose

• Management of diabetic ketoacidosis and perioperative glycemic control (under hospital settings)

• Use in combination with intermediate- or long-acting insulin for comprehensive glucose management

Mechanism of Action

Gensulin R mimics the action of endogenous human insulin. After administration, it promotes glucose uptake by muscle and adipose tissue and inhibits hepatic glucose production. As a short-acting insulin, it begins to act relatively quickly, helping to control blood glucose spikes after meals. Its predictable onset and duration of action make it a reliable option for mealtime insulin coverage and acute glucose control.

Dosage and Administration

• Gensulin R may be administered by subcutaneous injection, typically 30 minutes before meals.

• In hospital settings, it may also be given intravenously for rapid blood glucose control under strict medical supervision.

• Dosage is individualized based on blood glucose monitoring, dietary intake, physical activity, and clinical response.

• Injection sites should be rotated to reduce the risk of lipodystrophy.

All dosing and administration should be guided by a healthcare professional.

Use in Special Populations

• Elderly Patients: Increased susceptibility to hypoglycemia; careful dose adjustment is recommended.

• Renal or Hepatic Impairment: Reduced insulin requirements may occur; close monitoring is essential.

• Pregnancy and Lactation: Insulin is the treatment of choice for diabetes during pregnancy and breastfeeding when required.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

The most common side effect of Gensulin R is hypoglycemia, which may present with symptoms such as sweating, tremor, dizziness, hunger, headache, or confusion. Other possible side effects include:

• Weight gain

• Injection site reactions

• Lipodystrophy with repeated injections at the same site

• Rare allergic reactions

Proper education on insulin use and blood glucose monitoring helps minimize adverse effects.

Drug Interactions

Several medications may influence insulin action, including:

• Oral antidiabetic drugs

• Corticosteroids

• Beta-blockers

• Diuretics

• Thyroid hormones

Blood glucose should be monitored regularly when used alongside these medications.

Storage

• Store at 2°C–8°C in a refrigerator

• Do not freeze

• Protect from light

• Keep out of reach of children

Advantages of Gensulin R Injection

• Rapid onset for effective mealtime glucose control

• High purity insulin produced by recombinant DNA technology

• Flexible use in both outpatient and hospital settings

• Suitable for combination insulin therapy.