Gabarol CR Tablet 330 mg contains Pregabalin in a controlled-release (CR) formulation, designed to deliver long-lasting and consistent therapeutic effects. This higher-strength dosage is typically prescribed for patients requiring more intensive management of neuropathic pain, seizure disorders, or anxiety conditions. The controlled-release mechanism ensures gradual absorption of the medicine, reducing dosing frequency and improving patient convenience.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Pregabalin 330 mg (Controlled Release)
• Dosage Form: Controlled-release tablet

Indications

Gabarol CR Tablet 330 mg is indicated for the treatment of:

• Moderate to severe neuropathic pain (including diabetic neuropathy and post-herpetic neuralgia)
• Nerve pain associated with spinal cord injury
• Adjunctive therapy in partial seizures
• Generalized anxiety disorder (GAD)
• Fibromyalgia and other chronic pain conditions

Mechanism of Action

Pregabalin works by binding to voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P, which are involved in pain signaling and abnormal brain activity. The controlled-release formulation allows for a steady and prolonged effect, minimizing fluctuations in drug levels.

Dosage and Administration

• Take this medication exactly as prescribed by your doctor.
• Usually taken once daily, preferably after an evening meal.
• Swallow the tablet whole with water; do not crush, chew, or split it.
• Maintain a regular dosing schedule for best results.
• Do not stop the medication suddenly, as it may lead to withdrawal symptoms.

Benefits

• Provides sustained relief from chronic and nerve-related pain
• Suitable for patients needing higher-dose therapy
• Once-daily dosing improves treatment adherence
• Helps control seizures when used with other antiepileptic drugs
• Reduces anxiety and improves sleep quality
• Maintains stable blood levels, reducing side effects variability

Possible Side Effects

Common side effects include:

• Dizziness
• Drowsiness
• Fatigue
• Blurred vision
• Dry mouth
• Weight gain
• Swelling of hands, legs, or feet

These side effects are generally mild to moderate and may decrease with continued use. Seek medical advice if symptoms persist or worsen.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with kidney impairment; dose adjustment may be required.
• Avoid alcohol, as it may increase drowsiness and dizziness.
• Not recommended during pregnancy or breastfeeding unless prescribed by a doctor.
• May affect alertness; avoid driving or operating heavy machinery if affected.
• Inform your healthcare provider about any other medications or medical conditions.

Storage

• Store below 30°C in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children.