FXR Tablet contains Obeticholic Acid 5 mg, a selective farnesoid X receptor (FXR) agonist used in the management of chronic liver diseases associated with bile acid dysregulation. It helps improve liver function by reducing bile acid production, decreasing inflammation, and slowing the progression of liver fibrosis.

This lower-strength formulation is often used for dose initiation, adjustment, or maintenance therapy under specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

FXR Tablet 5 mg is indicated for:

• Primary biliary cholangitis (PBC)
• Chronic cholestatic liver disease
• Bile acid metabolism disorders
• Adjunct therapy in liver fibrosis management
• Patients intolerant to higher doses of Obeticholic Acid
• Combination therapy with ursodeoxycholic acid (UDCA) in selected cases

Mechanism of Action

Obeticholic Acid acts by targeting liver and intestinal receptors:

• Activates farnesoid X receptor (FXR)
• Suppresses bile acid synthesis in the liver
• Enhances bile acid transport and excretion
• Reduces hepatic inflammation and fibrosis progression
• Improves liver enzyme profile and cholestasis

Dosage & Administration

• Usual dose: 5 mg once daily or as directed by physician
• May be taken with or without food
• Dose adjustment may be required based on response and liver function
• Regular monitoring of liver function tests is essential
• Long-term therapy should be guided by a specialist

Side Effects

Common side effects may include:

• Itching (pruritus)
• Fatigue
• Abdominal discomfort
• Rash
• Dizziness
• Elevated cholesterol levels

Serious side effects may include worsening liver function in advanced liver disease.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under hepatologist supervision
• Not recommended in decompensated liver disease
• Monitor liver function regularly during therapy
• Use cautiously in patients with severe hepatic impairment
• May increase cholesterol levels in some patients
• Use during pregnancy only if clearly necessary
• Inform physician about all concurrent medications

Storage

• Store below 25°C in a cool and dry place
• Protect from moisture and light
• Keep in original packaging
• Keep out of reach of children
• Do not use after expiry date.