Fluclox DS Suspension 250 mg/5 ml contains Flucloxacillin Sodium, a narrow-spectrum penicillin antibiotic specially formulated as a double-strength oral suspension for children and patients who have difficulty swallowing tablets. It is highly effective against Gram-positive bacteria, particularly Staphylococcus aureus, including penicillinase-producing strains.

This pediatric-friendly formulation allows precise dosing and easy administration, making it ideal for moderate to severe bacterial infections. Flucloxacillin works by inhibiting bacterial cell wall synthesis, leading to bacterial death and rapid resolution of infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fluclox DS Suspension is indicated for the treatment of:

• Skin and soft tissue infections (cellulitis, boils, impetigo)
• Wound infections
• Bone and joint infections (osteomyelitis)
• Respiratory tract infections (tonsillitis, pneumonia)
• Ear infections (otitis media)
• Prophylactic use in surgical procedures at risk of Staphylococcus infection

Dosage and Administration

• Shake the bottle well before use.
• Dose is based on the child’s age and body weight:
  • Typical pediatric dose: 25–50 mg/kg/day divided into 3–4 doses.
• Measure doses accurately using a calibrated spoon or oral syringe.
• Can be taken with or without food; administration after meals may reduce stomach upset.
• Complete the full prescribed course even if symptoms improve early.

Mechanism of Action

Flucloxacillin is a beta-lactam antibiotic that:

• Binds to penicillin-binding proteins (PBPs) in bacterial cell walls
• Inhibits bacterial cell wall synthesis
• Leads to bacterial lysis and death

This bactericidal action ensures effective elimination of penicillinase-producing Staphylococcus aureus and other susceptible Gram-positive bacteria.

Precautions

• Use cautiously in patients with a history of penicillin allergy.
• Monitor liver function during prolonged therapy.
• Prolonged therapy may result in superinfection by resistant bacteria.
• Ensure adequate hydration to prevent kidney complications.
• Avoid skipping doses for consistent therapeutic effect.

Contraindications

Fluclox DS Suspension should not be used in:

• Patients allergic to penicillin or other beta-lactam antibiotics
• Individuals with a history of severe hypersensitivity reactions to Flucloxacillin

Side Effects

Common side effects:

• Nausea and vomiting
• Diarrhea
• Abdominal discomfort
• Skin rash or itching

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, angioedema)
• Liver dysfunction or cholestatic jaundice
• Severe diarrhea due to Clostridium difficile infection

Discontinue use and seek medical attention if serious adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants (e.g., warfarin)
• Probenecid may reduce renal excretion, increasing drug levels
• Live bacterial vaccines may be less effective

Always inform your healthcare provider about all medications the child is taking.

Storage

• Store below 25–30°C in a dry place
• Protect from light and moisture
• Keep the bottle tightly closed
• Keep out of reach of children.