Flubex DS Suspension 250 mg/5 ml contains Flucloxacillin Sodium, a penicillinase-resistant penicillin antibiotic specially formulated for pediatric use and for patients who have difficulty swallowing capsules. It is widely prescribed for the treatment of infections caused by penicillin-resistant Staphylococcus species and other susceptible gram-positive bacteria. The double-strength suspension ensures effective antibacterial therapy with convenient dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Flucloxacillin Sodium

• Strength: 250 mg per 5 ml suspension

Therapeutic Class

• Beta-lactam antibiotic

• Penicillinase-resistant penicillin

Pharmacology

Flucloxacillin exerts its bactericidal action by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins, blocking the formation of peptidoglycan cross-links essential for cell wall integrity. As a result, the bacterial cell wall becomes weak and susceptible to rupture, leading to bacterial death.

Unlike many penicillins, flucloxacillin is resistant to destruction by beta-lactamase enzymes produced by staphylococci. After oral administration, it is absorbed from the gastrointestinal tract, with improved absorption when taken on an empty stomach. It distributes well into skin, soft tissues, bone, and respiratory tract tissues, making it suitable for treating a variety of infections.

Indications

Flubex DS Suspension is indicated for the treatment of infections caused by flucloxacillin-sensitive organisms, including:

• Skin and soft tissue infections such as impetigo, boils, abscesses, and cellulitis

• Bone and joint infections, including osteomyelitis

• Respiratory tract infections

• Ear, nose, and throat infections

• Infected wounds and burns

• Other staphylococcal infections as advised by a physician

Dosage and Administration

• Dosage depends on the patient’s age, body weight, and severity of infection.

• The suspension should be taken on an empty stomach, ideally 1 hour before or 2 hours after meals, for optimal absorption.

• Shake the bottle well before each use.

• Duration of treatment should be completed as prescribed to prevent resistance.

Contraindications

• Hypersensitivity to flucloxacillin or other penicillin antibiotics

• History of flucloxacillin-associated jaundice or liver dysfunction

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with hepatic or renal impairment

• Prolonged use may lead to overgrowth of non-susceptible organisms

• Patients with a history of allergy to beta-lactam antibiotics should be carefully monitored

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, diarrhea

• Abdominal discomfort

• Skin rash or urticaria

Rare but serious reactions include allergic reactions, antibiotic-associated colitis, and cholestatic hepatitis.

Storage Conditions

• Store in a cool and dry place

• Reconstituted suspension should be stored as directed and used within the recommended time

• Keep out of reach of children.