Filmet Injection 500 mg/100 ml contains Metronidazole, a potent antimicrobial agent used for the treatment and prevention of infections caused by anaerobic bacteria and certain protozoa. This intravenous formulation is designed for use in hospitalized patients or in clinical settings where oral administration is not possible or rapid therapeutic action is required.

Metronidazole is highly effective against obligate anaerobes and protozoal organisms. By directly delivering the drug into the bloodstream, Filmet Injection ensures reliable bioavailability and rapid onset of action, making it a critical option in the management of serious and life-threatening infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Filmet Injection 500 mg/100 ml is indicated for:

• Severe anaerobic bacterial infections

• Intra-abdominal infections

• Pelvic and gynecological infections

• Septicemia caused by susceptible anaerobic organisms

• Brain abscess and central nervous system infections

• Bone and joint infections due to anaerobes

• Post-operative prophylaxis against anaerobic infections

• Protozoal infections when oral therapy is not feasible

Pharmacological Action

Metronidazole selectively enters anaerobic bacteria and protozoa, where it is reduced to active metabolites. These metabolites bind to microbial DNA, causing strand breakage and inhibition of nucleic acid synthesis, ultimately leading to cell death. This selective mechanism ensures potent antimicrobial activity with minimal effect on aerobic bacteria.

Dosage and Administration

• Filmet Injection is administered intravenously as a slow infusion.

• Dosage and duration depend on the type and severity of infection, patient age, body weight, and renal or hepatic function.

• It may be used alone or in combination with other antibacterial agents for mixed infections.

• Therapy should be switched to oral Metronidazole as soon as clinically appropriate.

Benefits

• Rapid and predictable therapeutic effect

• Suitable for critically ill patients

• Effective against a wide range of anaerobic pathogens

• Useful for both treatment and prophylaxis

• Ensures consistent drug levels in systemic circulation

Side Effects

Common side effects may include:

• Nausea or vomiting

• Headache

• Dizziness

• Injection site reactions

• Metallic taste

With prolonged use, rare adverse effects such as peripheral neuropathy or hypersensitivity reactions may occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Alcohol should be strictly avoided during treatment and for at least 48 hours after completion

• Use with caution in patients with liver impairment or neurological disorders

• Not recommended during the first trimester of pregnancy unless clearly necessary

• Regular monitoring is advised during prolonged therapy

Drug Interactions

Metronidazole may interact with alcohol, anticoagulants, lithium, and certain antiepileptic medicines. Concomitant use should be carefully monitored.

Storage

Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.

Filmet Injection 500 mg/100 ml provides reliable intravenous antimicrobial therapy for serious anaerobic and protozoal infections, supporting effective infection control in critical care and hospital settings.