Extals Tablet 50 mg contains Riluzole, a prescription medication used primarily for the management of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a progressive neurodegenerative disorder that affects nerve cells in the brain and spinal cord, leading to muscle weakness, loss of motor function, and ultimately respiratory failure. Extals Tablet 50 mg helps slow the progression of ALS by reducing neuronal damage and protecting motor neurons, thereby extending survival and improving quality of life.

Riluzole works by modulating glutamate neurotransmission, which is often elevated in ALS and contributes to excitotoxicity, a process that damages nerve cells. By inhibiting the release of glutamate and stabilizing neuronal activity, Extals helps protect motor neurons from progressive degeneration. The oral tablet formulation ensures convenient and consistent dosing for long-term management of this chronic condition.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features and Benefits

Active Ingredient:

• Riluzole 50 mg per tablet

Neuroprotective Action:

• Reduces glutamate-induced neuronal toxicity

• Slows the progression of ALS symptoms

• Supports preservation of motor function

Improved Survival:

• Clinical studies show Riluzole can prolong survival and delay the need for ventilatory support in ALS patients

Convenient Oral Formulation:

• Easy-to-swallow tablet

• Allows for consistent daily dosing

• Suitable for long-term therapy under medical supervision

Symptom Management:

• Helps maintain muscle strength and function

• Supports better mobility, speech, and swallowing abilities for a longer period

• Can improve overall quality of life for patients and caregivers

How It Works

Riluzole exerts its effects through multiple mechanisms:

1. Glutamate Inhibition: Reduces excessive release of glutamate, an excitatory neurotransmitter that contributes to motor neuron damage in ALS.

2. Sodium Channel Modulation: Partially blocks voltage-dependent sodium channels, stabilizing neurons and preventing overactivation.

3. Neuroprotection: Protects motor neurons from excitotoxicity, slowing the rate of neuronal death.

By targeting these pathways, Extals Tablet 50 mg helps delay disease progression and maintain motor function for a longer period.

Indications

Extals Tablet 50 mg is indicated for:

• Management of amyotrophic lateral sclerosis (ALS)

• Slowing functional decline in early and moderate stages of ALS

• Supporting prolonged survival and quality of life in ALS patients

Dosage and Administration

• Take orally as directed by your physician, usually one 50 mg tablet twice daily.

• Swallow the tablet whole, preferably on an empty stomach (1 hour before or 2 hours after meals) for optimal absorption.

• Do not alter the dosage without medical supervision.

• Regular monitoring of liver function is essential, as Riluzole may affect hepatic enzymes.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Safety Information

• Inform your doctor if you have liver disease, kidney impairment, or a history of hypersensitivity to Riluzole.

• Common side effects include nausea, fatigue, dizziness, and elevated liver enzymes.

• Rare but serious effects include hepatotoxicity and neutropenia. Regular blood tests are recommended.

• Avoid alcohol while taking Extals, as it may increase liver toxicity risk.

• Use caution when performing activities that require alertness, such as driving, due to potential dizziness or drowsiness.

Storage Instructions

• Store at room temperature, preferably below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.

Extals Tablet 50 mg provides an effective option for patients with ALS, offering neuroprotection, slowing disease progression, and supporting long-term survival. With proper medical supervision and consistent use, it helps maintain motor function and quality of life in this challenging neurodegenerative condition.