Etorac Tablet 10 mg contains Ketorolac Tromethamine, a potent non-steroidal anti-inflammatory drug (NSAID) with strong analgesic properties. It is primarily indicated for the short-term management of moderate to severe acute pain that requires analgesia at the opioid level, but without the associated risks of opioid dependence. Etorac Tablet is commonly prescribed in postoperative pain, musculoskeletal pain, and other acute painful conditions where rapid and effective pain relief is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Etorac Tablet 10 mg is indicated for the short-term treatment of:

• Moderate to severe acute pain

• Postoperative pain

• Pain associated with musculoskeletal disorders

• Dental pain

• Renal colic

• Acute pain following trauma or injury

Treatment duration should be limited to the shortest possible time, usually not exceeding 5 days.

Therapeutic Class

Non-Steroidal Anti-Inflammatory Drug (NSAID)

Pharmacology

Ketorolac Tromethamine exerts its analgesic, anti-inflammatory, and antipyretic effects by inhibiting the enzyme cyclooxygenase (COX-1 and COX-2). This inhibition reduces the synthesis of prostaglandins, which are key mediators involved in pain, inflammation, and fever. Unlike opioid analgesics, ketorolac does not act on opioid receptors and does not cause respiratory depression or dependence. Etorac Tablet provides effective pain relief comparable to opioids, making it a valuable option for acute pain management.

Dosage and Administration

The recommended oral dose of Etorac Tablet 10 mg in adults is:

• 10 mg every 4 to 6 hours as needed, depending on pain severity

• Maximum daily dose should not exceed 40 mg per day

Etorac Tablet is intended for short-term use only, generally up to 5 days. Dosage adjustments may be required in elderly patients or those with renal impairment. It should be taken with food or after meals to reduce gastrointestinal irritation.

Contraindications

Etorac Tablet 10 mg is contraindicated in patients with:

• Hypersensitivity to ketorolac or other NSAIDs

• Active or history of peptic ulcer disease or gastrointestinal bleeding

• Severe renal impairment

• Bleeding disorders or patients at high risk of bleeding

• Concurrent use with other NSAIDs

• Use during labor, delivery, or breastfeeding

Side Effects

Commonly reported side effects include:

• Gastrointestinal discomfort, nausea, or indigestion

• Abdominal pain

• Headache

• Dizziness

• Drowsiness

Serious adverse effects may include gastrointestinal bleeding, renal impairment, and increased risk of cardiovascular events, especially with prolonged use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Etorac Tablet should be used with caution in elderly patients due to increased risk of adverse effects

• Prolonged use increases the risk of gastrointestinal bleeding and renal toxicity

• Patients with cardiovascular disease, hypertension, or dehydration should be closely monitored

• Avoid alcohol consumption during treatment

• Concomitant use with anticoagulants or corticosteroids increases bleeding risk

Drug Interactions

Ketorolac may interact with:

• Anticoagulants and antiplatelet agents

• Other NSAIDs and aspirin

• Diuretics and antihypertensive drugs

• ACE inhibitors

• Lithium and methotrexate

These interactions may increase the risk of adverse effects or reduce therapeutic efficacy.

Use in Special Populations

• Pregnancy: Contraindicated, especially in the third trimester

• Lactation: Not recommended

• Geriatric Use: Lower doses and careful monitoring are advised

• Renal Impairment: Dose adjustment or avoidance is recommended

Storage Conditions

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.