Etorac MDT Tablet 10 mg contains Ketorolac Tromethamine, a potent non-steroidal anti-inflammatory drug (NSAID) formulated as a mouth-dissolving tablet (MDT) for rapid onset of action. It is indicated for the short-term management of moderate to severe acute pain where fast relief is required. The MDT formulation allows quick disintegration in the mouth without the need for water, making it especially convenient for patients who have difficulty swallowing conventional tablets.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Non-steroidal Anti-Inflammatory Drug (NSAID)

Indications

Etorac MDT Tablet 10 mg is indicated for the short-term treatment of:

• Moderate to severe acute pain

• Postoperative pain

• Acute musculoskeletal pain

• Dental pain

• Pain following minor surgical or diagnostic procedures

The total duration of therapy should not exceed 5 days, due to the increased risk of adverse effects with prolonged use.

Pharmacology

Ketorolac Tromethamine produces its analgesic and anti-inflammatory effects by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, resulting in reduced synthesis of prostaglandins. Prostaglandins are key mediators of pain, inflammation, and fever. By suppressing their production, Etorac MDT Tablet provides effective pain relief without sedative or addictive properties.
Ketorolac offers analgesic efficacy comparable to opioid analgesics but does not cause respiratory depression or dependence, making it a valuable non-opioid option for acute pain control.

Dosage and Administration

Adults

• 10 mg as a single dose or every 4 to 6 hours as needed

• Maximum daily dose: 40 mg/day

Elderly patients (≥65 years), renally impaired patients, or those weighing less than 50 kg

• Maximum daily dose: 20 mg/day

Duration of Use

• Treatment duration should not exceed 5 days

Dosage should be individualized based on patient condition, severity of pain, and clinical response.

Method of Administration

• Place the tablet on the tongue and allow it to dissolve completely

• The tablet dissolves rapidly and can be swallowed with saliva

• Water is not required, though it may be taken if preferred

• Do not chew or crush the tablet

Drug Interactions

• Concomitant use with other NSAIDs or aspirin may increase the risk of gastrointestinal bleeding

• Use with anticoagulants or antiplatelet agents may enhance bleeding risk

• May reduce the effectiveness of antihypertensive medications

• Concomitant use with nephrotoxic drugs may increase the risk of renal impairment

Contraindications

Etorac MDT Tablet 10 mg is contraindicated in patients with:

• Hypersensitivity to ketorolac or other NSAIDs

• Active or history of peptic ulcer disease or gastrointestinal bleeding

• Severe renal impairment

• Bleeding disorders or high risk of hemorrhage

• Use during labor, delivery, or perioperative pain in coronary artery bypass graft surgery

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Commonly reported side effects include:

• Nausea and vomiting

• Abdominal pain, dyspepsia

• Headache and dizziness

• Diarrhea

Serious adverse effects such as gastrointestinal bleeding, renal dysfunction, and hypersensitivity reactions may occur, particularly with prolonged use or higher doses.

Precautions and Warnings

• Intended for short-term use only

• Use the lowest effective dose for the shortest duration

• Monitor renal function in elderly and high-risk patients

• Avoid alcohol consumption during therapy to reduce gastrointestinal risk

Pregnancy and Lactation

• Contraindicated during pregnancy, especially in the third trimester

• Not recommended during breastfeeding due to potential risk to the infant

Storage Conditions

• Store below 30°C

• Protect from moisture and light

• Keep out of reach of children.