Esoprex MUPS Tablet 40 mg (Esomeprazole (MUPS preparation))

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Esoprex MUPS Tablet contains Esomeprazole 40 mg in a Multiple Unit Pellet System (MUPS) formulation. This advanced delivery system ensures uniform distribution of the drug in the gastrointestinal tract, providing consistent and effective acid suppression. It is widely used for the treatment of acid-related disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis.

The MUPS technology allows the tablet to disperse into multiple pellets in the stomach, enhancing absorption and reducing the risk of dose dumping, thereby improving therapeutic outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Esoprex MUPS Tablet is indicated for:

  • Gastroesophageal reflux disease (GERD)
  • Erosive esophagitis
  • Gastric and duodenal ulcers
  • Zollinger-Ellison syndrome
  • Prevention of NSAID-induced ulcers
  • Helicobacter pylori eradication (in combination with antibiotics)
  • Acid-related dyspepsia

Mechanism of Action

Esomeprazole works by reducing gastric acid production:

  • Inhibits the H⁺/K⁺ ATPase enzyme (proton pump) in gastric parietal cells
  • Blocks the final step of acid secretion
  • Provides long-lasting suppression of stomach acid
  • Promotes healing of ulcers and inflamed esophageal lining
  • MUPS formulation ensures gradual and uniform drug release

Dosage & Administration

  • Usual dose: 40 mg once daily or as prescribed
  • Take before meals, preferably in the morning
  • Tablet can be swallowed whole or dispersed in water before intake
  • Do not crush or chew the pellets
  • Follow physician instructions for duration of treatment
  • Suitable for patients who have difficulty swallowing conventional tablets

Side Effects

Common side effects may include:

  • Headache
  • Nausea
  • Abdominal pain
  • Diarrhea or constipation
  • Flatulence
  • Dry mouth

Long-term use may be associated with vitamin B12 deficiency, low magnesium levels, and increased risk of bone fractures.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

  • Use cautiously in patients with liver impairment
  • Long-term therapy should be monitored by a physician
  • May interact with medications such as clopidogrel and antifungals
  • Not recommended for prolonged self-medication
  • Inform physician about all current medications
  • Use during pregnancy and breastfeeding only if prescribed

Storage

  • Store below 25°C in a cool and dry place
  • Protect from moisture and light
  • Keep in original packaging
  • Keep out of reach of children. 

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Esoprex MUPS Tablet 40 mg (Esomeprazole (MUPS preparation))
Esoprex MUPS Tablet 40 mg (Esomeprazole (MUPS preparation))
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