Ecosprin Plus Tablet 75 mg+75 mg is a combination antiplatelet therapy containing Clopidogrel 75 mg and Aspirin (Acetylsalicylic Acid) 75 mg. This combination is primarily used for the prevention of cardiovascular events such as heart attacks, strokes, and thrombotic complications in patients with coronary artery disease, peripheral artery disease, or a history of myocardial infarction.

The dual mechanism of action—Clopidogrel inhibiting ADP-mediated platelet aggregation and Aspirin blocking thromboxane A2 production—provides enhanced antiplatelet effects, making it more effective than either drug alone. Ecosprin Plus Tablet is prescribed for patients at high risk of clot formation, including those undergoing percutaneous coronary intervention (PCI) or stent placement.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Clopidogrel: 75 mg

• Aspirin (Acetylsalicylic Acid): 75 mg

Indications

Ecosprin Plus Tablet 75 mg+75 mg is indicated for:

• Prevention of recurrent cardiovascular events in patients with a history of myocardial infarction or ischemic stroke

• Acute coronary syndrome (ACS) management, including unstable angina

• Post-percutaneous coronary intervention (PCI) or stent placement to prevent stent thrombosis

• Peripheral artery disease in patients at risk of thrombotic complications

• Secondary prevention of atherothrombotic events in high-risk cardiovascular patients

Mechanism of Action

Ecosprin Plus Tablet provides dual antiplatelet therapy (DAPT) through complementary mechanisms:

1. Clopidogrel:

   • Selectively and irreversibly inhibits the ADP receptor (P2Y12) on platelet surfaces.

   • Prevents ADP-mediated activation of platelets, reducing platelet aggregation.

2. Aspirin:

   • Irreversibly inhibits cyclooxygenase (COX-1) enzyme in platelets.

   • Reduces the synthesis of thromboxane A2, a potent promoter of platelet aggregation.

Together, Clopidogrel and Aspirin synergistically inhibit platelet aggregation, minimizing the risk of arterial clot formation and cardiovascular events.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The usual dose is one tablet once daily, preferably taken after meals to reduce gastrointestinal irritation. The tablet should be swallowed whole with water. Duration of therapy depends on the patient’s cardiovascular risk profile and the physician’s recommendations, especially in post-stent or acute coronary syndrome cases. Regular monitoring of blood pressure, kidney and liver function, and signs of bleeding is recommended.

Benefits of Ecosprin Plus Tablet 75 mg+75 mg

• Enhanced antiplatelet protection for high-risk cardiovascular patients

• Reduces the risk of heart attack, stroke, and stent thrombosis

• Combines two complementary mechanisms for synergistic efficacy

• Convenient once-daily dosing improves adherence

• Can be used in patients with coronary artery disease, peripheral artery disease, or post-PCI

• Helps maintain vascular health and reduce thrombotic events

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision

• Contraindicated in patients with active bleeding, hemorrhagic stroke, peptic ulcer, or hypersensitivity to Clopidogrel or Aspirin

• Increased risk of bleeding complications, including gastrointestinal bleeding

• Monitor for side effects such as easy bruising, nosebleeds, black stools, or prolonged bleeding

• Caution in patients taking anticoagulants, NSAIDs, or other antiplatelet agents

• Seek immediate medical attention for severe or unexplained bleeding

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Dual Antiplatelet Therapy / Cardiovascular Protective Agent / Antithrombotic.