Dysnov Tablet 10 mg contains Domperidone Maleate 10 mg, a dopamine D2 receptor antagonist widely used to manage gastrointestinal disorders such as nausea, vomiting, and delayed gastric emptying. Domperidone works by enhancing gastrointestinal motility and accelerating gastric emptying, while also acting on the chemoreceptor trigger zone to suppress signals that cause nausea and vomiting.

This makes Dysnov effective for patients suffering from functional dyspepsia, gastroesophageal reflux disease (GERD), post-operative nausea, chemotherapy-induced nausea, and other conditions involving delayed gastric emptying or frequent vomiting. Its oral tablet formulation ensures convenient and accurate dosing, allowing for flexible administration tailored to patient needs.

Dysnov is preferred for its rapid onset of action, efficacy, and favorable safety profile. Unlike some antiemetics, domperidone does not typically cause significant central nervous system side effects, as it does not readily cross the blood-brain barrier. This makes it suitable for patients who require nausea relief without sedation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dysnov Tablet 10 mg is indicated for:

• Nausea and vomiting of various causes, including post-operative, drug-induced, or gastrointestinal origin

• Gastroparesis or delayed gastric emptying, particularly in diabetic patients

• Functional dyspepsia, relieving bloating, early satiety, and discomfort

• Gastroesophageal reflux disease (GERD), to enhance esophageal clearance and gastric emptying

• Adjunct therapy in chemotherapy or radiotherapy-induced nausea

Key Benefits

• Provides rapid relief from nausea and vomiting

• Enhances gastric motility and accelerates gastric emptying

• Improves digestion and relief from bloating in functional dyspepsia

• Fewer central nervous system side effects due to limited penetration of the blood-brain barrier

• Convenient oral tablet formulation allows flexible dosing

Mechanism of Action

Domperidone Maleate is a selective dopamine D2 receptor antagonist that works through two primary mechanisms:

1. Central antiemetic action: It blocks dopamine receptors in the chemoreceptor trigger zone of the brain, reducing nausea and vomiting signals.

2. Peripheral prokinetic action: It enhances gastrointestinal motility by increasing the contraction of the stomach and intestinal muscles, speeding up the movement of food and reducing bloating and discomfort.

These combined actions make Dysnov effective for both symptomatic relief and underlying gastrointestinal motility issues.

Dosage and Administration

• The typical adult dose is 10 mg taken orally 3 times daily before meals.

• For children, dosing should be determined by a physician based on weight and clinical condition.

• Swallow the tablet with a full glass of water, and avoid crushing or chewing unless advised by a doctor.

• Follow the prescribed regimen consistently for optimal results.

Precautions

• Use with caution in patients with heart rhythm disorders, liver impairment, or gastrointestinal bleeding.

• Inform the physician about all medications, especially those affecting heart rhythm or dopamine pathways, to prevent interactions.

• Not recommended during pregnancy or breastfeeding unless prescribed by a healthcare professional.

• Seek medical advice if symptoms persist or worsen after prolonged use.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Dysnov Tablet 10 mg is generally well tolerated. Potential side effects include:

• Dry mouth or mild abdominal discomfort

• Headache or dizziness

• Rarely, diarrhea or constipation

• In very rare cases, cardiac arrhythmias may occur, particularly at high doses or in patients with pre-existing heart conditions

Most side effects are mild and resolve spontaneously. Regular monitoring is advised for prolonged therapy.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.