Dualvir Tablet contains Ledipasvir 90 mg and Sofosbuvir 400 mg, a fixed-dose combination antiviral medicine used for the treatment of chronic Hepatitis C virus (HCV) infection. This direct-acting antiviral (DAA) combination is highly effective against several genotypes of the Hepatitis C virus and has become a standard treatment option due to its high cure rates, convenient once-daily dosing, and favorable safety profile.

Dualvir Tablet works by targeting two essential proteins required for the replication of the Hepatitis C virus. By preventing the virus from multiplying, it helps eliminate the infection from the body, reduces liver inflammation, and lowers the risk of serious complications such as liver cirrhosis, liver failure, and hepatocellular carcinoma (liver cancer).

Treatment with Dualvir Tablet should always be initiated and monitored by a physician experienced in the management of chronic Hepatitis C infection. The duration of therapy depends on the patient's viral genotype, liver condition, previous treatment history, and other clinical factors.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Ledipasvir 90 mg
• Sofosbuvir 400 mg

How Dualvir Tablet Works

Dualvir Tablet combines two direct-acting antiviral agents that work at different stages of the Hepatitis C virus life cycle.

• Ledipasvir is an NS5A inhibitor that blocks the NS5A protein, which is essential for viral replication and assembly.
• Sofosbuvir is an NS5B RNA-dependent RNA polymerase inhibitor that prevents the virus from producing new viral RNA, thereby stopping viral replication.

Together, these medicines effectively suppress and eliminate the Hepatitis C virus, allowing the liver to heal and significantly increasing the likelihood of achieving a sustained virologic response (SVR), which is considered a cure for Hepatitis C.

Indications

Dualvir Tablet is indicated for the treatment of:

• Chronic Hepatitis C virus (HCV) infection
• HCV infection in adults and eligible adolescents, as determined by current treatment guidelines
• Selected patients with compensated cirrhosis or decompensated liver disease, in combination with other medicines when appropriate

Benefits of Dualvir Tablet

• Effectively treats chronic Hepatitis C infection
• High cure rates when taken as prescribed
• Prevents viral replication
• Helps reduce liver inflammation and damage
• Lowers the risk of cirrhosis, liver failure, and liver cancer
• Convenient once-daily oral dosing
• Generally well tolerated with a favorable safety profile

Dosage and Administration

Take Dualvir Tablet exactly as prescribed by your healthcare provider.

• Take one tablet once daily, with or without food, or as directed by your physician.
• Swallow the tablet whole with water.
• Take the medicine at the same time every day to maintain consistent drug levels.
• Complete the full course of treatment, even if you begin to feel better before it is finished.
• Do not miss doses, as this may reduce treatment effectiveness.

The treatment duration is typically 8 to 24 weeks, depending on the patient's clinical condition and treatment history.

Possible Side Effects

Like all medicines, Dualvir Tablet may cause side effects, although not everyone experiences them.

Common side effects include:

• Headache
• Fatigue
• Nausea
• Insomnia
• Diarrhea
• Weakness

Less common but serious side effects may include severe allergic reactions or worsening liver function in susceptible individuals. Patients with current or previous Hepatitis B infection should be carefully monitored, as reactivation of Hepatitis B has been reported during or after Hepatitis C treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

Before taking Dualvir Tablet, inform your healthcare provider if you:

• Have current or previous Hepatitis B infection
• Have liver disease other than Hepatitis C
• Have kidney disease or are receiving dialysis
• Have undergone a liver transplant
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking medications such as amiodarone, rifampicin, anticonvulsants, proton pump inhibitors, antacids, or herbal products like St. John's wort, as these may interact with the medicine

Regular monitoring of liver function and viral response may be recommended during treatment.

Storage

• Store below 30°C in a cool and dry place.
• Protect from moisture and direct sunlight.
• Keep the tablets in their original packaging until use.
• Keep out of the reach of children.
• Do not use after the expiry date printed on the package.