Dirozyl Tablet 400 mg contains Metronidazole, a potent nitroimidazole antibiotic widely used to treat anaerobic bacterial and protozoal infections. It is formulated for oral administration and is suitable for adults and children who can swallow tablets. Dirozyl Tablet is effective in managing a variety of infections, including gastrointestinal, gynecological, and skin infections, making it a versatile option for both hospital and outpatient care.

Metronidazole acts directly on susceptible microorganisms, disrupting their DNA and inhibiting nucleic acid synthesis, ultimately leading to cell death. It is particularly effective against Bacteroides, Clostridium species, Trichomonas, and Entamoeba histolytica, among others. Its broad-spectrum activity and reliable pharmacological profile make Dirozyl Tablet 400 mg a preferred choice for treating infections caused by anaerobic bacteria and protozoa.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Metronidazole: 400 mg per tablet

Indications

Dirozyl Tablet 400 mg is indicated for:

• Amebiasis, including intestinal and hepatic forms

• Giardiasis

• Trichomoniasis and other protozoal infections

• Bacterial vaginosis and gynecological infections

• Anaerobic bacterial infections of the gastrointestinal tract, skin, or soft tissues

• Prophylactic use in surgical procedures at risk of anaerobic infection

• Mixed infections caused by susceptible organisms

Mechanism of Action

Metronidazole penetrates bacterial and protozoal cells and undergoes reduction of its nitro group, generating reactive intermediates. These intermediates bind to microbial DNA, preventing nucleic acid synthesis and causing cell death. Its selective activity ensures effectiveness against anaerobes and protozoa while sparing aerobic bacteria, maintaining a relatively balanced microbiome.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The tablet should be swallowed with water and can be taken with or without food. Dosage depends on age, weight, severity, and type of infection. Completing the full course is essential to ensure infection resolution and prevent recurrence or resistance.

Benefits of Dirozyl Tablet 400 mg

• Broad-spectrum antimicrobial coverage

• Convenient oral administration for adults and older children

• Effective against protozoal and anaerobic bacterial infections

• Rapid relief of infection symptoms

• Suitable for outpatient therapy with consistent bioavailability

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use under medical supervision

• Avoid alcohol consumption during treatment due to risk of disulfiram-like reactions

• Caution in patients with hepatic or renal impairment

• Long-term use may lead to neurological side effects, including neuropathy and seizures

• Not recommended during the first trimester of pregnancy unless prescribed by a physician

• May interact with anticoagulants, lithium, or other medications; consult your physician

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Nitroimidazole Antibiotic.