Diasulin Injection 30%+70% combines 30% Regular Insulin Human (rapid-acting) with 70% Isophane Insulin Human (intermediate-acting) in a 40 IU/ml formulation. This premixed insulin is designed to manage both postprandial and fasting blood glucose in patients with type 1 or type 2 diabetes mellitus. The higher proportion of intermediate-acting insulin ensures extended basal coverage, while the rapid-acting component controls glucose spikes after meals. The 40 IU/ml concentration is ideal for patients requiring smaller or more precise insulin doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Regular Insulin Human 30% (rapid-acting)
• Isophane Insulin Human 70% (intermediate-acting)
• Strength: 40 IU/ml

Indications

Diasulin Injection 30%+70% is indicated for:

• Type 1 diabetes mellitus requiring insulin therapy
• Type 2 diabetes mellitus when oral antidiabetic agents are insufficient
• Blood glucose management in hospitalized patients or those with fluctuating glucose levels
• Patients needing both rapid post-meal and sustained basal insulin coverage

Mechanism of Action

• Regular Insulin Human: Rapidly lowers blood glucose by promoting cellular glucose uptake, inhibiting hepatic glucose production, and regulating protein and lipid metabolism.
• Isophane Insulin Human (NPH): Slowly releases insulin over 12–16 hours, providing prolonged basal glucose control.

The 30:70 ratio ensures both immediate postprandial control and long-lasting basal insulin coverage.

Dosage and Administration

• Administer subcutaneously as prescribed by a healthcare professional
• Dose individualized based on blood glucose monitoring, diet, and lifestyle
• Inject before meals for optimal postprandial glucose control
• Rotate injection sites to prevent lipodystrophy
• Do not mix with other insulins unless directed by a physician

Benefits

• Provides rapid post-meal and prolonged basal glucose control in one injection
• Reduces the need for multiple daily injections
• Supports better glycemic stability throughout the day
• Ideal for patients requiring lower or precise insulin doses
• Convenient premixed formulation improves adherence

Side Effects

Common side effects may include:

• Hypoglycemia (low blood sugar)
• Injection site reactions such as redness, swelling, or itching
• Mild weight gain

Rare side effects:

• Severe allergic reactions
• Lipodystrophy at repeated injection sites

Seek immediate medical attention for severe hypoglycemia or allergic reactions.

Precautions

• Regular blood glucose monitoring is essential
• Adjust dosage during illness, stress, or changes in diet or activity
• Use cautiously in patients with liver, kidney, or cardiovascular conditions
• Carry a source of fast-acting sugar to manage hypoglycemia

Contraindications

• Hypersensitivity to insulin or any component of the formulation
• Severe hypoglycemia

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral antidiabetic drugs, corticosteroids, beta-blockers, diuretics, and other medications affecting blood glucose
• Inform your healthcare provider about all medications currently being taken

Storage

• Store refrigerated at 2–8°C; do not freeze
• Protect from light and heat
• Once opened, in-use vials can be stored at room temperature (below 30°C) for up to 28 days
• Keep out of reach of children.