Dabiren Capsule 150 mg contains Dabigatran Etexilate Mesylate, a potent oral anticoagulant used to prevent and treat blood clots. Dabigatran is a direct thrombin inhibitor, which works by blocking thrombin (factor IIa), an essential enzyme in the blood clotting process. This prevents the conversion of fibrinogen to fibrin, reducing the risk of clot formation.

Dabiren Capsule is widely prescribed for patients with atrial fibrillation to prevent stroke and systemic embolism, and for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). Its oral formulation provides convenience and does not generally require routine blood monitoring in patients with normal kidney function.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন.

Composition

Each capsule contains:

• Dabigatran Etexilate Mesylate 150 mg

Mechanism of Action

Dabigatran is a prodrug that converts to active dabigatran in the body. Active dabigatran directly inhibits thrombin, preventing fibrin formation and clot development. This mechanism helps manage thromboembolic conditions while minimizing the risk of excessive bleeding compared to traditional anticoagulants.

Indications

Dabiren Capsule 150 mg is indicated for:

• Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation

• Treatment and prevention of recurrence of deep vein thrombosis (DVT)

• Treatment and prevention of pulmonary embolism (PE)

• Prevention of venous thromboembolism after hip or knee replacement surgery

Dosage and Administration

• The standard dose is 150 mg taken orally twice daily, or as prescribed by a healthcare professional.

• Swallow the capsule whole with water; do not crush or chew.

• Can be taken with or without food.

• Take at the same times each day to maintain consistent anticoagulant effect.

• Dosage adjustment may be required in patients with kidney impairment; follow doctor’s guidance.

Precautions

• Use with caution in patients with kidney or liver disease.

• Inform your doctor of any bleeding disorders or history of gastrointestinal ulcers.

• Not recommended for patients with mechanical heart valves.

• Pregnancy and breastfeeding: use only if prescribed by a healthcare professional.

• Avoid abrupt discontinuation to reduce the risk of thromboembolic events.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন.

Possible Side Effects

Common side effects may include:

• Easy bruising or minor bleeding (gums, nose)

• Prolonged bleeding from cuts

• Gastrointestinal discomfort, nausea, or indigestion

• Rare allergic reactions

Seek immediate medical attention if severe or unusual bleeding occurs.

Storage

• Store below 25°C in a cool, dry place

• Keep the container tightly closed and protected from moisture

• Keep out of reach of children

Dabiren Capsule 150 mg is a reliable and effective anticoagulant for preventing and managing blood clots. With proper medical supervision, it helps reduce the risk of stroke, DVT, and pulmonary embolism safely and efficiently.