Corangi Tablet 10 mg contains Nicorandil 10 mg, a potent anti-anginal medication used in the management of chronic stable angina pectoris. Nicorandil has a dual mechanism of action—it acts both as a nitrate and as a potassium channel opener—providing effective relief from chest pain while improving blood flow to the heart muscle.

Chronic stable angina occurs when the oxygen demand of the heart exceeds supply, usually due to narrowed coronary arteries. Symptoms include chest discomfort, pressure, or pain during physical activity or emotional stress. Nicorandil helps alleviate these symptoms by dilating both veins and arteries, reducing cardiac workload, and improving oxygen supply to the myocardium.

The dual action of Nicorandil allows it to relax smooth muscles in the coronary and systemic circulation. This reduces preload and afterload, lowers myocardial oxygen demand, and prevents episodes of angina. Unlike some other anti-anginal drugs, Nicorandil maintains stable blood pressure and has a favorable safety profile for long-term use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Corangi Tablet 10 mg is indicated for:

• Chronic stable angina pectoris

• Prevention of angina attacks in patients with coronary artery disease

• Adjunct therapy for patients not adequately controlled by beta-blockers or nitrates alone

Key Benefits

• Provides rapid and sustained relief from angina symptoms

• Improves exercise tolerance and daily activity capacity

• Dual mechanism of action ensures effective cardiac oxygenation

• Helps prevent recurrence of angina attacks

• Suitable for long-term management of chronic stable angina

Mechanism of Action

Nicorandil exerts its therapeutic effect through two complementary mechanisms:

1. Nitrate-like action: It releases nitric oxide, leading to vasodilation of veins and coronary arteries. This reduces preload and myocardial oxygen demand.

2. Potassium channel opening: It activates ATP-sensitive potassium channels in vascular smooth muscle, causing arterial vasodilation and reducing afterload.

By improving blood flow to the heart and decreasing oxygen demand, Nicorandil effectively prevents angina attacks.

Dosage and Administration

The usual recommended dose of Corangi Tablet 10 mg is determined by a physician based on the severity of angina and patient response. Tablets are typically taken once or twice daily, preferably with water.

Patients should follow their prescribed dosing schedule carefully. Swallow the tablet whole without crushing or chewing. Dose adjustments may be required in patients with kidney or liver impairment.

Precautions

• Avoid abrupt discontinuation without medical advice.

• Use cautiously in patients with low blood pressure or heart failure.

• Not recommended during pregnancy or breastfeeding unless prescribed by a physician.

• Inform your doctor about any other medications being taken, especially nitrates or antihypertensives.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Corangi Tablet 10 mg is generally well tolerated, but some patients may experience:

• Headache

• Flushing

• Dizziness or lightheadedness

• Nausea

• Hypotension (low blood pressure)

Most side effects are mild and transient, often resolving with continued use or dose adjustment.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.