Coavlon Tablet combines Artemether 20 mg and Lumefantrine 120 mg, a powerful antimalarial therapy designed to treat acute uncomplicated malaria caused by Plasmodium falciparum. This combination provides rapid parasite clearance and sustained therapeutic effect, making it a first-line treatment for malaria in many regions. Artemether acts quickly to reduce the parasite load, while Lumefantrine maintains prolonged action to prevent relapse.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Coavlon Tablet 20 mg + 120 mg is indicated for:

• Treatment of acute uncomplicated malaria caused by Plasmodium falciparum
• Mixed infections with Plasmodium falciparum and Plasmodium vivax where appropriate
• Cases requiring combination therapy to reduce the risk of drug resistance

Mechanism of Action

• Artemether: A fast-acting derivative of artemisinin, it produces free radicals within malaria parasites, leading to rapid parasite death.
• Lumefantrine: Acts more slowly by interfering with parasite detoxification processes, ensuring sustained antimalarial activity.

The combination ensures rapid symptom relief while preventing recurrence of infection.

Dosage and Administration

• Take the tablet as prescribed by a physician, usually in a six-dose regimen over three days
• Tablets should be taken with food, preferably fatty meals, to enhance absorption
• Swallow whole with water; do not crush or chew
• Complete the full course even if symptoms improve to prevent relapse or resistance

Benefits

• Rapid clearance of malaria parasites
• Reduces fever and other malaria symptoms quickly
• Prevents recurrence and reduces the risk of drug resistance
• Convenient combination therapy in a single tablet formulation

Side Effects

Common side effects may include:

• Nausea or vomiting
• Headache
• Dizziness or fatigue
• Abdominal discomfort

Rare but serious side effects:

• Allergic reactions
• Arrhythmias or prolonged QT interval
• Severe skin reactions

Seek immediate medical attention if severe reactions occur.

Precautions

• Use with caution in patients with heart disease or a history of arrhythmias
• Avoid self-medication; follow the full prescribed course
• Not recommended in severe malaria or cerebral malaria without hospital supervision
• Inform your doctor about all other medications to prevent drug interactions
• Regular monitoring may be advised in patients with liver or kidney disorders

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only under medical supervision; generally avoided in the first trimester unless necessary
• Lactation: Consult a healthcare provider before use
• Children: Pediatric dosing should be strictly followed according to body weight

Storage

• Store below 30°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children.