Cefa-4 Injection 500 mg/vial contains Cefepime Hydrochloride, a fourth-generation cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria. This formulation is ideal for mild to moderate bacterial infections or for initiating therapy before escalating to higher doses if required.

Cefepime works by inhibiting bacterial cell wall synthesis, leading to bacterial lysis and death. The injectable form ensures rapid therapeutic action, making it suitable for hospitalized patients and situations where oral therapy is not feasible.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Broad-spectrum activity against Gram-positive and Gram-negative bacteria
• Effective for mild to moderate bacterial infections
• Rapid onset of action due to injectable formulation
• Useful for hospitalized patients or patients unable to take oral antibiotics
• Reliable and well-tolerated

Indications

Cefa-4 Injection 500 mg/vial is indicated for:

• Lower respiratory tract infections
• Urinary tract infections
• Skin and soft tissue infections
• Intra-abdominal infections
• Bacteremia and sepsis
• Febrile neutropenia

Mechanism of Action

Cefepime is a β-lactam antibiotic that:

• Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
• Disrupts bacterial cell wall integrity, causing cell lysis
• Exhibits bactericidal activity against a wide spectrum of pathogens

Dosage and Administration

• Administered by a healthcare professional via intravenous (IV) or intramuscular (IM) injection
• Typical adult dose: 500 mg every 12 hours, adjustable based on infection severity and renal function
• Pediatric dosing is weight-based and determined by a physician
• Dose adjustment required in patients with renal impairment
• Administer IV slowly to reduce local irritation

Side Effects

Common side effects:

• Injection site pain, redness, or swelling
• Nausea, vomiting, or diarrhea
• Mild headache

Rare side effects:

• Allergic reactions including rash, itching, or anaphylaxis
• Liver or kidney function alterations
• Blood disorders such as neutropenia or thrombocytopenia in rare cases

Precautions and Warnings

• Use cautiously in patients with a history of penicillin or cephalosporin allergy
• Monitor kidney function during prolonged therapy
• Observe for signs of superinfection with long-term use
• Adjust dosage in patients with renal impairment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Hypersensitivity to Cefepime, other cephalosporins, or β-lactam antibiotics
• History of severe allergic reactions to penicillin

Storage Instructions

• Store below 30°C in a dry, dark place
• Protect from light
• Keep out of reach of children.