Cefa-4 Injection 2 gm/vial contains Cefepime Hydrochloride, a fourth-generation cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria. It is highly effective in treating severe, complicated, and resistant bacterial infections. Cefepime works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death, making it a potent option for hospital settings and serious infections.

This higher-dose formulation is suitable for critically ill patients or severe infections where rapid and sustained therapeutic levels are needed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Broad-spectrum activity against Gram-positive and Gram-negative bacteria, including resistant strains
• Effective for severe and complicated infections
• Injectable form ensures fast therapeutic action
• Useful for hospitalized patients and acute infections
• Well-tolerated with a reliable safety profile

Indications

Cefa-4 Injection 2 gm/vial is indicated for:

• Severe lower respiratory tract infections
• Complicated urinary tract infections
• Skin and soft tissue infections
• Intra-abdominal infections
• Septicemia and bacteremia
• Febrile neutropenia and immunocompromised patients

Mechanism of Action

Cefepime is a β-lactam antibiotic that:

• Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
• Causes cell wall disruption and bacterial lysis
• Exhibits bactericidal activity against a wide spectrum of pathogens

Dosage and Administration

• Administered by healthcare professionals via intravenous (IV) or intramuscular (IM) injection
• Typical adult dose: 2 g every 12 hours, adjustable according to infection severity and renal function
• Pediatric dosing is weight-based and determined by a physician
• Dose adjustment is required in patients with renal impairment
• Administer IV slowly to minimize local irritation

Side Effects

Common side effects:

• Injection site pain, redness, or swelling
• Nausea, vomiting, or diarrhea
• Mild headache

Rare side effects:

• Allergic reactions such as rash, itching, or anaphylaxis
• Liver or kidney function alterations
• Blood disorders like neutropenia or thrombocytopenia in rare cases

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with history of penicillin or cephalosporin allergy
• Monitor renal function during prolonged therapy
• Observe for superinfections with long-term use
• Adjust dosing in patients with renal impairment

Contraindications

• Hypersensitivity to Cefepime, other cephalosporins, or β-lactam antibiotics
• History of severe allergic reactions to penicillin

Storage Instructions

• Store below 30°C in a dry, dark place
• Protect from light
• Keep out of reach of children.