Canazole Tablet contains Fluconazole 150 mg, a triazole antifungal agent designed to treat and prevent a variety of fungal infections. Fluconazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, which disrupts fungal growth and replication.

This 150 mg dose is commonly used for adults and older children, particularly in the treatment of vaginal candidiasis and other moderate fungal infections, providing effective symptom relief and preventing recurrence.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Canazole Tablet 150 mg is indicated for:

• Vaginal candidiasis in adult women
• Oropharyngeal candidiasis
• Treatment of systemic fungal infections caused by susceptible fungi
• Prophylaxis of fungal infections in immunocompromised patients
• Management of recurrent or persistent fungal infections that require a medium-strength dose

Composition

• Active Ingredient: Fluconazole
• Strength: 150 mg per tablet
• Dosage Form: Oral tablet

Mechanism of Action

Fluconazole is a triazole antifungal agent. Its mechanism includes:

• Inhibiting lanosterol 14α-demethylase, an enzyme required for ergosterol synthesis
• Disrupting the fungal cell membrane, causing leakage of cellular contents and fungal cell death
• Providing broad-spectrum antifungal activity against Candida species and other susceptible fungi

This action ensures effective management of fungal infections while minimizing adverse effects on human cells.

Dosage & Administration

• Adults: সাধারণত 150 mg as a single dose for vaginal candidiasis, or as prescribed for other infections
• Children: Dose is weight-based; use only under medical supervision
• Swallow the tablet with water; it can be taken with or without food
• Complete the full course to prevent recurrence or resistance
• Dose adjustments may be necessary in renal impairment

Side Effects

Canazole Tablet 150 mg is generally well tolerated. Possible side effects include:

• Nausea or vomiting
• Diarrhea or stomach discomfort
• Headache
• Skin rash or mild allergic reactions
• Rare: elevated liver enzymes or severe allergic reactions

Seek medical advice if side effects persist or worsen.

Precautions & Warnings

• Use with caution in patients with liver or kidney disease
• Monitor liver function during prolonged therapy
• Avoid concurrent use with drugs that prolong the QT interval or interact with CYP3A4
• Not recommended for routine prophylaxis without medical supervision

Drug Interactions

• May interact with warfarin, phenytoin, cyclosporine, certain statins, or other CYP3A4 substrates
• Inform your healthcare provider about all medications being taken

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly necessary under medical supervision
• Lactation: Avoid breastfeeding or seek medical advice
• Elderly: Monitor renal and liver function; adjust dose if needed
• Pediatrics: Safe under supervision with weight-based dosing

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep the tablet in its original packaging until use
• Keep out of reach of children.