Calvasc Tablet 10 mg contains Amlodipine Besilate, a long-acting calcium channel blocker from the dihydropyridine class, used for the management of hypertension and angina pectoris. Amlodipine is known for its potent vasodilatory effects, which help relax blood vessels, lower blood pressure, and improve coronary blood flow.

Calvasc 10 mg is particularly suitable for patients whose blood pressure is not adequately controlled with lower doses or those experiencing persistent angina symptoms. Its once-daily dosing provides a stable therapeutic effect throughout the day, making it convenient for long-term management of cardiovascular conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amlodipine Besilate 10 mg

Mechanism of Action

Amlodipine works by blocking L-type calcium channels in vascular smooth muscle and cardiac muscle:

• Vasodilation: Reduces peripheral vascular resistance, lowering both systolic and diastolic blood pressure

• Coronary Blood Flow Improvement: Enhances oxygen delivery to the heart muscle, relieving ischemia

• Reduction of Myocardial Oxygen Demand: Decreases cardiac workload, helping prevent angina attacks

• Long-Acting Effect: Slow onset and sustained duration ensure 24-hour blood pressure control

This dual effect on the vascular system and cardiac muscle makes Calvasc 10 mg an effective choice for both hypertension and angina management.

Indications

Calvasc Tablet 10 mg is indicated for:

• Essential hypertension – to control high blood pressure and reduce cardiovascular risk

• Chronic stable angina – prevention of angina attacks and improvement of exercise tolerance

• Vasospastic (Prinzmetal’s) angina – relief of chest pain caused by coronary artery spasm

• Hypertensive patients at risk of heart attack, stroke, or heart failure

Benefits

• Effective Blood Pressure Reduction: Lowers elevated blood pressure and prevents long-term complications

• Relieves Angina Symptoms: Reduces frequency and severity of chest pain

• Improves Coronary Circulation: Enhances myocardial oxygen supply

• Convenient Once-Daily Dosing: Ensures adherence and steady therapeutic levels

• Well-Tolerated: Minimal central nervous system effects, suitable for prolonged use

• Cardiovascular Protection: Helps reduce the risk of heart attack, stroke, and other complications of hypertension

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• Adults: 1 tablet (10 mg) orally once daily, preferably at the same time each day

• Can be taken with or without food

• For patients not responding to 5 mg, the dose may be increased to 10 mg as per physician guidance

• Elderly or patients with liver impairment may require careful dose adjustment

• Regular monitoring of blood pressure, heart rate, and renal function is recommended

Safety and Precautions

• Common side effects: headache, dizziness, flushing, peripheral edema (ankle swelling), and fatigue

• Rare side effects: palpitations, hypotension, or liver enzyme abnormalities

• Contraindicated in patients with severe hypotension, cardiogenic shock, or hypersensitivity to Amlodipine

• Use with caution in patients with severe aortic stenosis, heart failure, or liver disease

• Pregnant or breastfeeding women should take the medication only under medical supervision

• Avoid abrupt discontinuation to prevent rebound hypertension or worsening angina.