Cabergol Tablet 0.5 mg contains Cabergoline, a long-acting dopamine agonist used primarily to treat disorders associated with elevated prolactin levels (hyperprolactinemia). It effectively reduces prolactin secretion from the pituitary gland, helping manage conditions such as prolactin-secreting pituitary adenomas, amenorrhea, galactorrhea, and infertility related to hormonal imbalance.
Cabergoline works by stimulating dopamine D2 receptors in the pituitary gland, which inhibits prolactin release. Its high selectivity and long half-life allow for a convenient dosing schedule, improving patient adherence.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Key Benefits
-
Reduces elevated prolactin levels efficiently
-
Helps restore normal menstrual cycles and fertility in women
-
Manages symptoms like galactorrhea (inappropriate lactation)
-
Long-acting formulation allows for flexible dosing (once or twice weekly)
-
Well-tolerated with a favorable safety profile
Indications
Cabergol Tablet 0.5 mg is indicated for:
-
Hyperprolactinemia due to pituitary adenomas or idiopathic causes
-
Galactorrhea in women and men
-
Amenorrhea or infertility related to elevated prolactin levels
-
Adjunct therapy for prolactin-related hormonal disorders
Mechanism of Action
Cabergoline is a selective dopamine D2 receptor agonist:
-
Stimulates dopamine receptors in the anterior pituitary
-
Inhibits prolactin synthesis and secretion
-
Reduces prolactin-induced effects on the reproductive system, restoring normal hormonal balance
Dosage and Administration
-
Take as prescribed by a physician, usually 0.25–0.5 mg twice weekly or per individual dosing schedule
-
Swallow the tablet whole with water, preferably after a meal
-
Dosage adjustments may be necessary based on serum prolactin levels and tolerance
-
Avoid abrupt discontinuation without consulting a healthcare provider
Side Effects
Common side effects:
-
Nausea, vomiting, or gastrointestinal discomfort
-
Headache or dizziness
-
Fatigue or mild hypotension
Rare side effects:
-
Heart valve disorders with long-term high-dose use
-
Psychiatric symptoms such as mood changes or hallucinations
-
Allergic reactions including rash or swelling
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Precautions and Warnings
-
Monitor blood pressure and cardiac function during long-term therapy
-
Use caution in patients with pre-existing heart valve disease, psychiatric disorders, or liver impairment
-
Not recommended during pregnancy unless prescribed by a physician
-
Inform your doctor of all medications to avoid interactions, especially with other dopamine agonists
Contraindications
-
Hypersensitivity to Cabergoline or ergot derivatives
-
Uncontrolled hypertension
-
History of cardiac valvular disorders
-
Pregnancy or breastfeeding without medical supervision
Storage Instructions
-
Store at room temperature below 30°C
-
Protect from moisture and direct sunlight
-
Keep out of reach of children.