Bevastim Injection 100 mg/4 ml contains Bevacizumab, a recombinant humanized monoclonal antibody that works as an anti-angiogenic agent. It is widely used in oncology to treat various types of cancers by inhibiting the formation of new blood vessels (angiogenesis) that tumors need for growth and survival. This targeted therapy helps slow down tumor progression and enhances the effectiveness of other cancer treatments such as chemotherapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Bevacizumab 100 mg per 4 ml vial
• Dosage Form: Sterile solution for intravenous infusion

Mechanism of Action

Bevacizumab specifically binds to vascular endothelial growth factor (VEGF), a protein responsible for the formation of new blood vessels. By blocking VEGF, Bevastim prevents the development of blood vessels that supply oxygen and nutrients to tumors. This action restricts tumor growth and may lead to tumor shrinkage over time.

Indications

Bevastim Injection is indicated for the treatment of multiple cancers, including:

• Metastatic colorectal cancer
• Non-small cell lung cancer
• Glioblastoma (a type of brain tumor)
• Metastatic renal cell carcinoma
• Cervical cancer
• Ovarian, fallopian tube, or primary peritoneal cancer

It is usually administered in combination with other chemotherapy agents depending on the type and stage of cancer.

Dosage and Administration

• Administered as an intravenous infusion under the supervision of a qualified healthcare professional
• Dosage depends on body weight, type of cancer, and treatment protocol
• Infusion duration and frequency are determined by the treating physician
• Patients should be monitored closely during administration for any infusion-related reactions

Precautions

• Use with caution in patients with hypertension, bleeding disorders, or recent surgery
• May impair wound healing; treatment should be paused before and after surgical procedures
• Regular monitoring of blood pressure and kidney function is recommended
• Not recommended during pregnancy due to potential risk to the fetus

Side Effects

Common side effects may include:

• Hypertension (high blood pressure)
• Fatigue and weakness
• Bleeding or hemorrhage
• Proteinuria (protein in urine)
• Headache

Serious but less common side effects:

• Gastrointestinal perforation
• Thromboembolic events
• Severe infusion reactions

Patients should seek immediate medical attention if severe adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a refrigerator at 2°C to 8°C
• Do not freeze or shake
• Keep in original packaging to protect from light
• Keep out of reach of children

Conclusion

Bevastim Injection 100 mg/4 ml is an effective targeted cancer therapy that plays a crucial role in managing various malignancies. By inhibiting tumor blood supply, it helps control cancer progression and improves treatment outcomes when used as part of combination therapy. Proper medical supervision and monitoring are essential to ensure safety and effectiveness.