Avlosef Pediatric Drop contains Cephradine, a first-generation cephalosporin antibiotic widely used in children to treat a variety of bacterial infections. It is formulated as an easy-to-administer oral drop, making it suitable for infants and young children who have difficulty swallowing tablets or capsules.
Cephradine works by killing bacteria through inhibition of cell wall synthesis, ultimately leading to bacterial cell death. It is effective against both Gram-positive and some Gram-negative organisms.
Indications
Avlosef Pediatric Drop is prescribed for the treatment of infections caused by susceptible bacteria, including:
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Upper respiratory tract infections (pharyngitis, tonsillitis, sinusitis, otitis media)
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Lower respiratory tract infections (bronchitis, pneumonia)
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Urinary tract infections (cystitis, urethritis, pyelonephritis)
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Skin and soft tissue infections (cellulitis, abscess, impetigo)
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Other bacterial infections as directed by a physician
Composition
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Active Ingredient: Cephradine
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Strength: 125 mg per 1.25 ml
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Dosage Form: Pediatric oral drops
Mechanism of Action
Cephradine acts by inhibiting bacterial cell wall synthesis. It interferes with the formation of peptidoglycan, an essential component of the bacterial cell wall. This causes weakening and rupture of the cell wall, resulting in bacterial death.
Dosage & Administration
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Children: সাধারণত 25–50 mg/kg/day in divided doses
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Severe infections (e.g., otitis media): 75–100 mg/kg/day বিভক্ত ডোজে
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The dosage should be adjusted based on the child’s weight, age, and severity of infection
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Administer using a calibrated dropper for accurate dosing
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Can be taken with or without food
Always follow the physician’s prescription strictly.
Side Effects
Avlosef Pediatric Drop is generally well tolerated. However, some side effects may occur:
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Nausea, vomiting, diarrhea
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Abdominal discomfort
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Skin rash or allergic reactions
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Rare: dizziness, hypersensitivity reactions
Seek medical attention if severe allergic symptoms appear.
Precautions & Warnings
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Use with caution in patients with penicillin or cephalosporin allergy
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Dose adjustment may be required in renal impairment
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Complete the full course of treatment to prevent resistance
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Avoid unnecessary use to reduce antibiotic resistance
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Use in Special Populations
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Pregnancy: Use only if clearly needed
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Lactation: Small amounts may pass into breast milk; generally considered safe
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Children: Specifically formulated for pediatric use
Storage
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Store in a cool, dry place below 25°C
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Protect from light
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Keep out of reach of children.