Arthanib XR Tablet 11 mg contains Tofacitinib, an extended-release (XR) formulation of a Janus kinase (JAK) inhibitor used to manage chronic autoimmune and inflammatory diseases. The extended-release design allows the medication to be released gradually over 24 hours, providing consistent therapeutic effects with the convenience of once-daily dosing. Tofacitinib works by blocking JAK enzymes involved in the immune response, reducing inflammation and helping relieve symptoms such as joint pain, swelling, stiffness, and fatigue. Arthanib XR Tablet is prescribed for adults with certain autoimmune conditions when conventional therapies have not provided adequate results or are not well tolerated. It should always be used under the supervision of a qualified healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Arthanib XR Tablet 11 mg is indicated for the treatment of:

• Moderate to severe rheumatoid arthritis in adults with an inadequate response or intolerance to methotrexate.
• Active psoriatic arthritis, either alone or in combination with non-biologic disease-modifying antirheumatic drugs (DMARDs).
• Moderate to severe ulcerative colitis in appropriate adult patients.
• Active ankylosing spondylitis in eligible adults.
• Other approved autoimmune inflammatory disorders as determined by the treating physician.

How Arthanib XR Tablet Works

Tofacitinib selectively inhibits Janus kinase (JAK) enzymes, mainly JAK1 and JAK3, while partially inhibiting JAK2. These enzymes play a key role in transmitting signals from inflammatory cytokines within immune cells. By blocking these pathways, Arthanib XR reduces excessive immune activity, decreases inflammation, and helps prevent ongoing damage to joints and other affected tissues. The extended-release formulation provides a steady release of the medication throughout the day, maintaining effective drug levels while reducing the need for multiple daily doses.

Benefits of Arthanib XR Tablet 11 mg

• Provides convenient once-daily dosing.
• Helps reduce joint pain, swelling, and stiffness.
• Improves physical function and daily activities.
• Slows progression of joint damage in rheumatoid arthritis.
• Helps control symptoms of ulcerative colitis, including diarrhea and rectal bleeding.
• Offers consistent therapeutic drug levels through extended-release technology.
• Suitable for patients requiring long-term management of autoimmune diseases.

Dosage and Administration

Take Arthanib XR Tablet exactly as prescribed by your physician. Swallow the tablet whole with water. Do not crush, split, or chew the extended-release tablet, as this may affect the controlled release of the medicine. It may be taken with or without food. The dosage should be individualized based on the patient's condition, treatment response, and kidney or liver function. Do not stop taking the medicine without consulting your healthcare provider.

Possible Side Effects

Like all medicines, Arthanib XR Tablet may cause side effects, although not everyone experiences them.

Common side effects include:

• Upper respiratory tract infections
• Headache
• Diarrhea
• Nausea
• Elevated cholesterol levels
• Mild increases in liver enzymes

Serious but less common side effects may include:

• Serious bacterial, viral, or fungal infections
• Blood clots
• Major cardiovascular events
• Gastrointestinal perforation
• Low blood cell counts
• Increased risk of certain cancers

Seek immediate medical attention if you develop fever, persistent cough, chest pain, sudden swelling of the legs, shortness of breath, or signs of severe infection.

Precautions and Warnings

Before using Arthanib XR Tablet, inform your doctor if you have:

• Active or recurrent infections
• Tuberculosis or exposure to tuberculosis
• Liver or kidney disease
• A history of blood clots or cardiovascular disease
• Cancer or a weakened immune system
• Pregnancy, planning pregnancy, or breastfeeding

Regular monitoring of complete blood count, liver function, kidney function, lipid profile, and screening for tuberculosis is recommended before and during treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep out of the reach of children.

Disclaimer

Arthanib XR Tablet 11 mg is a prescription-only medicine and should be used only under medical supervision. Follow your healthcare provider's instructions carefully and attend regular follow-up appointments for monitoring. Do not share this medication with others, even if they have similar symptoms.