Aloglip Tablet 6.25 mg contains Alogliptin Benzoate, an oral antidiabetic agent belonging to the class of DPP-4 (dipeptidyl peptidase-4) inhibitors. It is used in the management of type 2 diabetes mellitus, particularly in patients who require a lower dose due to renal impairment or as part of combination therapy.

Alogliptin works by enhancing the body’s natural incretin hormones, which play a key role in regulating blood glucose levels. It increases insulin secretion in response to meals and reduces glucagon release, helping to maintain better glycemic control without causing significant hypoglycemia when used alone.

This lower-strength formulation (6.25 mg) is commonly used in patients with reduced kidney function, where dose adjustment is necessary to ensure safe and effective treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Helps improve blood sugar control in type 2 diabetes
• Suitable for patients requiring renal dose adjustment
• Enhances meal-dependent insulin secretion
• Reduces glucagon levels and hepatic glucose production
• Low risk of hypoglycemia when used as monotherapy

Indications

Aloglip Tablet 6.25 mg is indicated for:

• Type 2 diabetes mellitus in adults
• Patients with moderate to severe renal impairment requiring dose reduction
• Use as monotherapy or in combination with:
  • Metformin
  • Insulin
  • Sulfonylureas
  • Other antidiabetic agents (as prescribed)

Mechanism of Action

Alogliptin inhibits the DPP-4 enzyme, which normally breaks down incretin hormones (GLP-1 and GIP). By blocking this enzyme, it increases active incretin levels, leading to:

• Increased insulin release after meals
• Decreased glucagon secretion
• Reduced liver glucose production
• Improved overall glycemic control

Dosage & Administration

• Dose should be determined by a physician based on kidney function
• Typically taken once daily
• Can be taken with or without food
• Swallow the tablet whole with water
• Regular monitoring of blood glucose is recommended

Possible Side Effects

Common side effects may include:

• Headache
• Nasopharyngitis (common cold symptoms)
• Upper respiratory tract infection
• Mild gastrointestinal discomfort

Rare but serious side effects:

• Pancreatitis (severe abdominal pain)
• Severe allergic reactions
• Joint pain or skin reactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Dose adjustment required in renal impairment
• Not recommended for type 1 diabetes or diabetic ketoacidosis
• Monitor blood glucose regularly during therapy
• Use cautiously in patients with a history of pancreatitis
• Consult a doctor before use during pregnancy or breastfeeding

Storage Instructions

• Store below 30°C
• Protect from moisture and heat
• Keep in original packaging
• Keep out of reach of children.