Acupain Injection 30 mg/ml (Ketorolac Tromethamine)

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Acupain Injection 30 mg/ml contains Ketorolac Tromethamine, a potent non-steroidal anti-inflammatory drug (NSAID) used for the short-term management of moderate to severe acute pain. It is commonly administered in clinical settings such as hospitals or emergency care where rapid pain relief is required. Acupain is especially effective in managing postoperative pain and other acute painful conditions, offering an alternative to opioid analgesics.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Acupain Injection is indicated for:

  • Short-term management of moderate to severe acute pain
  • Postoperative pain relief
  • Musculoskeletal pain
  • Renal colic and other acute pain conditions
  • Pain where opioid-sparing treatment is preferred

Mechanism of Action

Ketorolac Tromethamine works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of prostaglandins. Prostaglandins are key mediators of inflammation and pain. By reducing their production, Acupain effectively alleviates pain and inflammation.


Dosage and Administration

  • Administered by a healthcare professional via intramuscular (IM) or intravenous (IV) injection
  • Dosage depends on the patient’s age, weight, and clinical condition
  • Typically used for short durations (not exceeding 5 days) due to risk of adverse effects
  • Patients may be switched to oral therapy if needed after initial injection

Side Effects

Common side effects may include:

  • Nausea and vomiting
  • Dizziness
  • Drowsiness
  • Injection site pain

Serious side effects include:

  • Gastrointestinal bleeding or ulceration
  • Kidney impairment
  • Increased risk of bleeding
  • Allergic reactions such as rash, swelling, or breathing difficulty

Immediate medical attention is required if severe side effects occur.


Precautions and Warnings

  • Not recommended for long-term use due to increased risk of serious adverse effects
  • Use cautiously in elderly patients and those with kidney, liver, or heart disease
  • Contraindicated in patients with active peptic ulcer disease or recent gastrointestinal bleeding
  • Avoid use before or after major surgery with high bleeding risk
  • Not recommended during pregnancy, especially in the third trimester
  • Monitor kidney function and signs of bleeding during treatment

Drug Interactions

Acupain Injection may interact with:

  • Other NSAIDs or aspirin
  • Anticoagulants (e.g., warfarin)
  • Corticosteroids
  • Diuretics and antihypertensive drugs
  • Certain antidepressants (SSRIs)

Always inform your healthcare provider about all medications you are taking.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Conclusion

Acupain Injection 30 mg/ml (Ketorolac Tromethamine) is a highly effective option for short-term management of moderate to severe pain, particularly in postoperative and acute care settings. When used under proper medical supervision, it provides rapid and reliable pain relief while minimizing the need for opioid medications.

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Acupain Injection 30 mg/ml (Ketorolac Tromethamine)
Acupain Injection 30 mg/ml (Ketorolac Tromethamine)
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