Acmecilin Injection 500 mg/vial contains Ampicillin Sodium, a broad-spectrum penicillin-class antibiotic used for the treatment of bacterial infections caused by susceptible organisms. It is a reliable parenteral option for patients who cannot take oral antibiotics or require rapid therapeutic levels in the bloodstream. This injectable formulation ensures precise dosing, fast onset of action, and effective treatment of various systemic infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active ingredient: Ampicillin Sodium 500 mg per vial

Pharmacological Action

Ampicillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. This leads to the disruption of bacterial cell wall formation, resulting in bacterial cell death. Ampicillin is active against a wide range of gram-positive and gram-negative bacteria and is particularly effective against susceptible strains of Streptococcus, Enterococcus, Escherichia coli, Haemophilus influenzae, and Salmonella species.

Indications

Acmecilin Injection is indicated for the treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections such as pneumonia, bronchitis, and tonsillitis

• Urinary tract infections

• Skin and soft tissue infections

• Gastrointestinal infections including enteritis and typhoid

• Septicemia and other systemic infections

• Meningitis caused by susceptible organisms

• Prophylaxis in certain surgical procedures to prevent post-operative infections

Dosage and Administration

• Adults: The usual dose ranges from 500 mg to 1 g every 6 hours depending on the severity and site of infection

• Children: Dosage is based on body weight and clinical condition, as prescribed by a physician

• The injection can be administered intravenously (IV) or intramuscularly (IM) after reconstitution with a suitable diluent

• Infuse slowly over 3–5 minutes for IV use to reduce the risk of adverse reactions

The duration of therapy depends on the type and severity of infection and should be determined by a healthcare professional. Completing the full course is essential to prevent bacterial resistance.

Benefits and Advantages

• Broad-spectrum antibiotic effective against gram-positive and gram-negative bacteria

• Fast-acting parenteral formulation suitable for severe or systemic infections

• Can be used when oral administration is not feasible

• Proven efficacy in both pediatric and adult patients

• Useful in hospital settings for serious infections

Safety and Precautions

Acmecilin Injection is generally well tolerated. Common side effects may include mild diarrhea, nausea, vomiting, rash, or local irritation at the injection site. Serious allergic reactions are rare but may occur in sensitive individuals.

• Contraindicated in patients with a history of hypersensitivity to penicillins or beta-lactam antibiotics

• Use with caution in patients with renal impairment

• Monitor for signs of superinfection with prolonged use

• Pregnant or breastfeeding women should use under medical supervision

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Concurrent use with other beta-lactam antibiotics, aminoglycosides, or oral anticoagulants should be monitored by a physician to avoid potential interactions.

Storage

• Store below 30°C

• Protect from light and moisture

• Keep out of reach of children

• Use the reconstituted solution immediately or follow recommended storage guidelines

Pack Information

Acmecilin Injection 500 mg/vial is supplied as a sterile, dry powder in single-dose vials for reconstitution, ensuring stability, potency, and ease of administration.